ArticlePlastic and reconstructive surgery. Global open2022
Implant-based Breast Reconstruction after Mastectomy for Breast Cancer: A Systematic Review and Meta-analysis.
Article in Plastic and reconstructive surgery. Global open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 27 citations in OpenAlex.
- Effect of a Multimedia-Assisted Informed Consent Procedure on the Information Gain of Patients Undergoing Mastectomy and Implant-Based Reconstruction.Aesthetic plastic surgery · 2026Trial
- Prepectoral Breast Reconstruction with Polyurethane-Coated Implants: A 117-Patient Single-Center Study with Objective Cosmetic Evaluation.Aesthetic plastic surgery · 2026Article
- Cannabis Use and Outcomes in Breast Surgery.Plastic and reconstructive surgery. Global open · 2026Article
- Impact of breast implant presence and type on mean glandular dose calculations.Polish journal of radiology · 2026Article
- Implant Plane Does Not Seem to Impact Shoulder Function after Direct-to-Implant Breast Reconstruction in Non-Radiated Patients: A Randomized Controlled Trial.Archives of plastic surgery · 2025Article
- CAR-T cell therapy and reconstructive oncologic surgery in peripheral solid tumors-A narrative review.Cell reports. Medicine · 2025Review
- Direct-to-Implant Prepectoral Breast Reconstruction with a Novel Collagen Matrix Following Nipple-Sparing Mastectomy: A Case Report.Reports (MDPI) · 2025Article
- Predictive Modeling of Human Skin Deformation and Growth During Tissue Expansion in Postmastectomy Breast Reconstruction.Journal of biomechanical engineering · 2025Article
- Complications and Burden of 2-Stage Tissue Expander to Implant-Based Reconstructive Surgery: A Single-Center Retrospective Study.Plastic surgery (Oakville, Ont.) · 2025Article
- 3D-printed CoSi/PCL composite scaffold with NIR-II photothermal ability and enhanced adipogenic activity for breast reconstruction after mastectomy.Materials today. Bio · 2025Article
- Outcomes of ADM-Assisted Implant-based Breast Reconstructions According to Division Types of the Pectoralis Major Muscle.Aesthetic plastic surgery · 2025Article
- Silicone Breast Implant Rupture Triggered by Infection Leading to Skin Ulceration: A Case Report.Cureus · 2024Article
- Article
- Methods in regression analysis in surgical oncology research-best practice guidelines.Journal of surgical oncology · 2024Article
- From standard therapies to monoclonal antibodies and immune checkpoint inhibitors - an update for reconstructive surgeons on common oncological cases.Frontiers in immunology · 2024Review
- Regional Implicit Racial Bias and Rates of Breast Reconstruction, Complications, and Cost Among US Patients With Breast Cancer.JAMA network open · 2023Article
- Medical Imaging of Inflammations and Infections of Breast Implants.Diagnostics (Basel, Switzerland) · 2023Review
- Silicone Implant Surface Roughness, Friction, and Wear.Surface topography : metrology and properties · 2023Article
- Implant-based versus Autologous Reconstruction after Mastectomy for Breast Cancer: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2022Article
- Implant-based Breast Reconstruction after Mastectomy for Breast Cancer: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Women undergoing implant-based reconstruction (IBR) after mastectomy for breast cancer have numerous options, including timing of IBR relative to radiation and chemotherapy, implant materials, anatomic planes, and use of human acellular dermal matrices. We conducted a systematic review to evaluate these options. Methods: We searched Medline, Embase, Cochrane CENTRAL, CINAHL, and ClinicalTrials.gov for studies, from inception to March 23, 2021, without language restriction. We assessed risk of bias and strength of evidence (SoE) using standard methods. Results: We screened 15,936 citations. Thirty-six mostly high or moderate risk of bias studies (48,419 patients) met criteria. Timing of IBR before or after radiation may result in comparable physical, psychosocial, and sexual well-being, and satisfaction with breasts (all low SoE), and probably comparable risks of implant failure/loss or explantation (moderate SoE). No studies addressed timing relative to chemotherapy. Silicone and saline implants may result in clinically comparable satisfaction with breasts (low SoE). Whether the implant is in the prepectoral or total submuscular plane may not impact risk of infections (low SoE). Acellular dermal matrix use probably increases the risk of implant failure/loss or need for explant surgery (moderate SoE) and may increase the risk of infections (low SoE). Risks of seroma and unplanned repeat surgeries for revision are probably comparable (moderate SoE), and risk of necrosis may be comparable with or without human acellular dermal matrices (low SoE). Conclusions: Evidence regarding IBR options is mostly of low SoE. New high-quality research is needed, especially for timing, implant materials, and anatomic planes of implant placement.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.