Evidence map›Paper›PMID 35317349›Full record

ArticleVirus evolution2022

Whole-genome analysis to determine the rate and patterns of intra-subtype reassortment among influenza type-A viruses in Africa.

Grace Nabakooza, Andrzej Pastusiak, David Patrick Kateete, Julius Julian Lutwama, John Mulindwa Kitayimbwa, Simon David William Frost

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Grace NabakoozaDepartment of Immunology and Molecular Biology, Makerere University, Old Mulago Hill Road, P.O Box 7072, Kampala, Uganda.ORCID https://orcid.org/0000-0003-4565-3227
Andrzej PastusiakMicrosoft Research, 14820 NE 36th Street, Redmond, WA 98052, USA.
David Patrick KateeteDepartment of Immunology and Molecular Biology, Makerere University, Old Mulago Hill Road, P.O Box 7072, Kampala, Uganda.
Julius Julian LutwamaDepartment of Arbovirology Emerging & Re-Emerging Infectious Diseases, Uganda Virus Research Institute (UVRI), Plot No: 51-59, Nakiwogo Road, P.O. Box 49, Entebbe, Uganda.
John Mulindwa KitayimbwaUVRI Centre of Excellence in Infection and Immunity Research and Training (MUII-Plus), Makerere University, Plot No: 51-59 Nakiwogo Road, P.O. Box 49, Entebbe, Uganda.
Simon David William FrostMicrosoft Research, 14820 NE 36th Street, Redmond, WA 98052, USA.
Makerere University · UGMicrosoft (United States) · USUganda Virus Research Institute · UG

Funding

Wellcome Trust
6 · The paper itself

Abstract

Influenza type-A viruses (IAVs) present a global burden of human respiratory infections and mortality. Genome reassortment is an important mechanism through which epidemiologically novel influenza viruses emerge and a core step in the safe reassortment-incompetent live-attenuated influenza vaccine development. Currently, there are no data on the rate, spatial and temporal distribution, and role of reassortment in the evolution and diversification of IAVs circulating in Africa. We aimed to detect intra-subtype reassortment among Africa pandemic H1N1pdm09 (2009-10), seasonal H1N1pdm09 (2011-20), and seasonal H3N2 viruses and characterize the genomic architecture and temporal and spatial distribution patterns of the resulting reassortants. Our study was nested within the Uganda National Influenza Surveillance Programme. Next-generation sequencing was used to generate whole genomes (WGs) from 234 H1N1pdm09 (

Indexed as

AfricaevolutiongenomicsH1N1pdm09H3N2influenza Aintra-subtype reassortmentphylogeneticsreassortmenttransmissionUgandawhole-genome sequencing

Identifiers

PMID35317349
PMCPMC8933723
OpenAlexW4210495884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.