Evidence map›Paper›PMID 35316363›Full record

ArticleEuropean radiology2022

How artificial intelligence improves radiological interpretation in suspected pulmonary embolism.

Alexandre Ben Cheikh, Guillaume Gorincour, Hubert Nivet, Julien May, Mylene Seux, Paul Calame, Vivien Thomson, Eric Delabrousse, Amandine Crombé

Open access · bronzeAbstract read
In one paragraph

Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
19.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Alexandre Ben CheikhIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France.
Guillaume GorincourIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France. g.gorincour@imadis.fr.ORCID http://orcid.org/0000-0002-4926-1063
Hubert NivetIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France.
Julien MayIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France.
Mylene SeuxIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France.
Paul CalameDepartment of Radiology, Centre Hospitalier Universitaire de Besançon, Besançon, France.
Vivien ThomsonIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France.
Eric DelabrousseDepartment of Radiology, Centre Hospitalier Universitaire de Besançon, Besançon, France.
Amandine CrombéIMADIS, 48 Rue Quivogne, 69002, Lyon, Bordeaux, Marseille, France.
Générale de Santé · FRInserm · FRGorky Institute of World Literature · RUInstitut d'Imagerie Biomédicale · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate and compare the diagnostic performances of a commercialized artificial intelligence (AI) algorithm for diagnosing pulmonary embolism (PE) on CT pulmonary angiogram (CTPA) with those of emergency radiologists in routine clinical practice.

methodsThis was an IRB-approved retrospective multicentric study including patients with suspected PE from September to December 2019 (i.e., during a preliminary evaluation period of an approved AI algorithm). CTPA quality and conclusions by emergency radiologists were retrieved from radiological reports. The gold standard was a retrospective review of CTPA, radiological and clinical reports, AI outputs, and patient outcomes. Diagnostic performance metrics for AI and radiologists were assessed in the entire cohort and depending on CTPA quality.

resultsOverall, 1202 patients were included (median age: 66.2 years). PE prevalence was 15.8% (190/1202). The AI algorithm detected 219 suspicious PEs, of which 176 were true PEs, including 19 true PEs missed by radiologists. In the cohort, the highest sensitivity and negative predictive values (NPVs) were obtained with AI (92.6% versus 90% and 98.6% versus 98.1%, respectively), while the highest specificity and positive predictive value (PPV) were found with radiologists (99.1% versus 95.8% and 95% versus 80.4%, respectively). Accuracy, specificity, and PPV were significantly higher for radiologists except in subcohorts with poor-to-average injection quality. Radiologists positively evaluated the AI algorithm to improve their diagnostic comfort (55/79 [69.6%]).

conclusionInstead of replacing radiologists, AI for PE detection appears to be a safety net in emergency radiology practice due to high sensitivity and NPV, thereby increasing the self-confidence of radiologists. KEY POINTS: • Both the AI algorithm and emergency radiologists showed excellent performance in diagnosing PE on CTPA (sensitivity and specificity ≥ 90%; accuracy ≥ 95%). • The AI algorithm for PE detection can help increase the sensitivity and NPV of emergency radiologists in clinical practice, especially in cases of poor-to-moderate injection quality. • Emergency radiologists recommended the use of AI for PE detection in satisfaction surveys to increase their confidence and comfort in their final diagnosis.

Indexed as

Pulmonary EmbolismRadiologyAgedAngiographyArtificial IntelligenceHumansRetrospective StudiesArtificial intelligenceComputed tomography angiographyPredictive value of testsPulmonary embolismSensitivity and specificity

Identifiers

PMID35316363
PMCPMC8938594
OpenAlexW4220777473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.