Evidence map›Paper›PMID 35316162›Full record

ArticleCell cycle (Georgetown, Tex.)2022

Improvement of autophagic flux mediates the protection of hydrogen sulfide against arecoline-elicited neurotoxicity in PC12 cells.

Sheng-Lan Gao, Yi-Yun Tang, Jia-Mei Jiang, Wei Zou, Ping Zhang, Xiao-Qing Tang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Role of cystathionine-β-synthase and hydrogen sulfide in down syndrome.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sheng-Lan GaoClinical Research Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, GD, China.
Yi-Yun TangDepartment of Physiology, Institute of Neuroscience, Hengyang Medical School, University of South China, Hengyang, HN, China.
Jia-Mei JiangThe First Affiliated Hospital, Institute of Neurology, Hengyang Medical School, University of South China, Hengyang, HN, China.
Wei ZouThe Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, HN, China.
Ping ZhangThe Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, HN, China.
Xiao-Qing TangDepartment of Physiology, Institute of Neuroscience, Hengyang Medical School, University of South China, Hengyang, HN, China.
University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arecoline, the most abundant alkaloid of the areca nut, induces toxicity to neurons. Hydrogen sulfide (H

Indexed as

Hydrogen SulfideAnimalsApoptosisArecolineAutophagyEndoplasmic Reticulum StressPC12 CellsRatsArecolineHydrogen SulfidearecolineAutophagic fluxhydrogen sulfideneurotoxicity

Identifiers

PMID35316162
PMCPMC9037498
OpenAlexW4220663934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.