Evidence map›Paper›PMID 35316153›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension.

Rowena J Jones, Eckart M D D De Bie, Emily Groves, Kasia I Zalewska, Emilia M Swietlik, Carmen M Treacy, Jennifer M Martin, Gary Polwarth, Wei Li, Jingxu Guo and 25 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  10. Pulmonary hypertension post-liver transplant: A case report.World journal of gastrointestinal surgery · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Immunosuppressive Treatment for an anti-UInternal medicine (Tokyo, Japan) · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Is It Still "Idiopathic"? Features of Autoimmunity in Idiopathic Pulmonary Arterial Hypertension.American journal of respiratory and critical care medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors at 16 institutions in 5 countries.

Rowena J JonesHeart and Lung Research Institute.ORCID 0000-0002-4551-2320
Eckart M D D De BieHeart and Lung Research Institute.ORCID 0000-0002-1595-1226
Emily GrovesHeart and Lung Research Institute.
Kasia I ZalewskaHeart and Lung Research Institute.
Emilia M SwietlikHeart and Lung Research Institute.
Carmen M TreacyHeart and Lung Research Institute.
Jennifer M MartinHeart and Lung Research Institute.
Gary PolwarthRoyal Papworth Hospital, and.
Wei LiHeart and Lung Research Institute.
Jingxu GuoHeart and Lung Research Institute.
Helen E BaxendaleRoyal Papworth Hospital, and.
Stephen ColemanMedical Research Council Biostatistics Unit.
Natalia SavinykhCambridge Biomedical Research Centre Phenotyping Hub, Department of Medicine, University of Cambridge.
J Gerry CoghlanRoyal Free London National Health Service Foundation Trust, London, United Kingdom.
Paul A CorrisFreeman Hospital, Newcastle-upon-Tyne, United Kingdom.
Luke S HowardHammersmith Hospital, London, United Kingdom.
Martin K JohnsonScottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
Colin ChurchScottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
David G KielySheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Allan LawrieDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
James L LordanFreeman Hospital, Newcastle-upon-Tyne, United Kingdom.
Robert V Mackenzie RossRoyal United Hospitals Bath National Health Service Foundation Trust, Bath, United Kingdom.
Joanna Pepke ZabaRoyal Papworth Hospital, and.
Martin R WilkinsNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.ORCID 0000-0003-3926-1171
S John WortRoyal Brompton Hospital, London, United Kingdom.
Edoardo FiorilloIstituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Cagliari, Italy.
Valeria OrrùIstituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Cagliari, Italy.
Francesco CuccaUniversity of Sassari, Sassari, Italy; and.
Christopher J RhodesNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.
Stefan GräfHeart and Lung Research Institute.
Nicholas W MorrellHeart and Lung Research Institute.
Eoin F McKinneyCambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Chris WallaceHeart and Lung Research Institute.ORCID 0000-0001-9755-1703
Mark ToshnerHeart and Lung Research Institute.ORCID 0000-0002-3969-6143
UK National Cohort Study of Idiopathic and Heritable PAH Consortium
Lung Institute · USPapworth Hospital · GBFreeman Hospital · GBGolden Jubilee National Hospital · GBImperial College London · GBInstitute of Genetic and Biomedical Research · ITNational Health Service · GBCambridge School · PTHammersmith Hospital · GBMedical Research Council · GBMRC Epidemiology Unit · GBRoyal Brompton Hospital · GBRoyal Hallamshire Hospital · GBUniversity of Cambridge · GBUniversity of Sassari · ITUniversity of Sheffield · GB

Funding

British Heart Foundation CH/09/001/25945British Heart Foundation FS/15/59/31839British Heart Foundation FS/18/52/33808British Heart Foundation FS/SBSRF/20/31005British Heart Foundation PG/17/1/32532British Heart Foundation PG/17/58/33134British Heart Foundation RE/18/4/34215British Heart Foundation SP/18/10/33975Medical Research Council MC_UU_00002/4Medical Research Council MR/K020919/1Wellcome Trust 107881Wellcome Trust WT107881
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutoimmunityHypertension, PulmonaryAutoantibodiesCross-Sectional StudiesFamilial Primary Pulmonary HypertensionHumansAutoantibodiesautoantibodiesautoimmuneBMPR2IPAHpulmonary arterial hypertension

Identifiers

PMID35316153
PMCPMC7613913
OpenAlexW4220755510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.