Evidence map›Paper›PMID 35316142›Full record

ArticleGut microbes

An

Jaclyn Y Lock, Mariaelena Caboni, Philip Strandwitz, Madeleine Morrissette, Kevin DiBona, Brian A Joughin, Kim Lewis, Rebecca L Carrier

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Identification of hub genes associated withWorld journal of diabetes · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jaclyn Y LockDepartment of Bioengineering, Northeastern University, Boston, Massachusetts, USA.
Mariaelena CaboniAntimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, Massachusetts, USA.
Philip StrandwitzAntimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, Massachusetts, USA.
Madeleine MorrissetteAntimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, Massachusetts, USA.
Kevin DiBonaDepartment of Biochemistry, Northeastern University, Boston, Massachusetts, USA.
Brian A JoughinThe Koch Institute for Integrative Cancer Research at Mit and the Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massacusetts, USA.
Kim LewisAntimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, Massachusetts, USA.
Rebecca L CarrierDepartment of Bioengineering, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0003-3002-7098
Northeastern University · USMassachusetts Institute of Technology · US

Funding

GuMI: New In Vitro Platforms to Parse the Human Gut Epithelial-Microbiome-Immune AxisR01EB021908 · NIBIB · NORTHEASTERN UNIVERSITY · PI CARRIER, REBECCA L, GRIFFITH, LINDA G · 2016 to 2020
$5.2M
Systems approaches to understanding the relationships between genotype, signaling, and therapeutic efficacyU01CA215798 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HAAS, WILHELM, HAIGIS, KEVIN · 2017 to 2021
$3.7M
Impact of Lipids on Compound Absorption: Mechanistic Studies and ModelingR01GM098117 · NIGMS · NORTHEASTERN UNIVERSITY · PI CARRIER, REBECCA L · 2012 to 2021
$3.3M
NCI NIH HHS U01 CA215798NIBIB NIH HHS R01 EB021908NIGMS NIH HHS R01 GM098117
6 · The paper itself

Abstract

Considerable effort has been put forth to understand mechanisms by which the microbiota modulates and responds to inflammation. Here, we explored whether oxidation metabolites produced by the host during inflammation, sodium nitrate and trimethylamine oxide, impact the composition of a human stool bacterial population in a gut simulator. We then assessed whether an immune-competent

Indexed as

Gastrointestinal MicrobiomeMicrobiotaAnimalsBacteriaCytokinesHumansInflammationMammalsCytokinesanaerobic respirationendotoxinEnterobacteriaceaeGut microbiomegut simulatorinflammationinnate immune cellsintestinal model

Identifiers

PMID35316142
PMCPMC8942420
OpenAlexW4225408477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.