Evidence map›Paper›PMID 35315788›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs.

Grace Nauman, Nichole M Danzl, Jaeyop Lee, Chiara Borsotti, Rachel Madley, Jianing Fu, Markus A Hölzl, Alexander Dahmani, Akaitz Dorronsoro Gonzalez, Éstefania Chavez and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 2 countries.

Grace NaumanColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.ORCID 0000-0002-1633-5150
Nichole M DanzlColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.
Jaeyop LeeDepartment of Microbiology and Immunology, Columbia University Medical Center, Columbia University, New York, NY.
Chiara BorsottiColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.ORCID 0000-0001-9704-0647
Rachel MadleyColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.
Jianing FuColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.
Markus A HölzlColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.ORCID 0000-0002-3333-7967
Alexander DahmaniColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.
Akaitz Dorronsoro GonzalezColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.ORCID 0000-0001-6141-8484
Éstefania ChavezColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.
Sean R CampbellColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.ORCID 0000-0002-5567-6265
Suxiao YangColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY.
Prakash SatwaniColumbia University Vagelos College of Physicians and Surgeons, Columbia University, New York, NY.ORCID 0000-0003-3867-9066
Kang LiuDepartment of Microbiology and Immunology, Columbia University Medical Center, Columbia University, New York, NY.
Megan SykesColumbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, Columbia University, New York, NY; megan.sykes@columbia.edu.
Columbia University Irving Medical Center · US

Funding

XENOGRAFT TOLERANCE THROUGH MIXED CHIMERISMP01AI045897 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Megan Sykes · 2000 to 2026
$71.9M
Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systemsU01DK123559 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ANDERSON, MARK S, PARENT, AUDREY · 2019 to 2023
$4.3M
Mice with autologous human T1D-derived immune systems and iPSC-derived beta cellsUC4DK104207 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SYKES, MEGAN · 2014 to 2014
$3.8M
Columbia University Graduate Training Program in Microbiology and ImmunologyT32AI106711 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nicholas Arpaia, Uttiya Basu · 2014 to 2026
$2.1M
Immune Response to iPSC-Derived Beta Cells in Type 1 DiabetesR01DK103585 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SYKES, MEGAN · 2015 to 2018
$1.8M
Thymic negative selection in human T1D immune systemsR21AI146828 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SYKES, MEGAN · 2019 to 2020
$437k
Becton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413k
Cell intrinsic immunopathology of Type I diabetes in humanized miceF32DK095539 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DANZL, NICHOLE MARIE · 2012 to 2014
$173k
NCRR NIH HHS S10 RR027050NIAID NIH HHS P01 AI045897NIAID NIH HHS R21 AI146828NIAID NIH HHS T32 AI106711NIDDK NIH HHS F32 DK095539NIDDK NIH HHS R01 DK103585NIDDK NIH HHS U01 DK123559NIDDK NIH HHS UC4 DK104207
6 · The paper itself

Abstract

Immunodeficient mice reconstituted with immune systems from patients, or personalized immune (PI) mice, are powerful tools for understanding human disease. Compared with immunodeficient mice transplanted with human fetal thymus tissue and fetal liver-derived CD34

Indexed as

Bone MarrowHematopoietic Stem Cell TransplantationAnimalsBone Marrow CellsHematopoietic Stem CellsHumansLiverMice

Identifiers

PMID35315788
PMCPMC8976823
OpenAlexW4220926424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.