Evidence map›Paper›PMID 35315692›Full record

ReviewInfection and immunity2022

A Resourceful Race: Bacterial Scavenging of Host Sulfur Metabolism during Colonization.

Paige J Kies, Neal D Hammer

Abstract readReview
In one paragraph

Review in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Crosstalk in the cold: host-microbe interactions in insect diapause.Annals of the Entomological Society of America · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Raman signatures ofFrontiers in microbiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Mechanism of Mongolian Medicine Batri-7 onJournal of inflammation research · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paige J KiesDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.
Neal D HammerDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.ORCID 0000-0001-6148-7850

Funding

Elucidating strategies of Staphylococcus aureus nutrient sulfur acquisition during infectionR01AI139074 · NIAID · MICHIGAN STATE UNIVERSITY · PI HAMMER, NEAL D. · 2019 to 2024
$2.4M
Examining host-derived glutathione as a sulfur source for Staphylococcus aureus during infectionR21AI142517 · NIAID · MICHIGAN STATE UNIVERSITY · PI HAMMER, NEAL D. · 2019 to 2020
$426k
HHS | National Institutes of Health (NIH) R01AI139074HHS | National Institutes of Health (NIH) R21AI142517NIAID NIH HHS R01 AI139074NIAID NIH HHS R21 AI142517
6 · The paper itself

Abstract

Sulfur is a requirement for life. Therefore, both the host and colonizing bacteria must regulate sulfur metabolism in a coordinated fashion to meet cellular demands. The host environment is a rich source of organic and inorganic sulfur metabolites that are utilized in critical physiological processes such as redox homeostasis and cellular signaling. As such, modulating enzymes dedicated to sulfur metabolite biosynthesis plays a vital role in host fitness. This is exemplified from a molecular standpoint through layered regulation of this machinery at the transcriptional, translational, and posttranslational levels. With such a diverse metabolite pool available, pathogens and symbionts have evolved multiple mechanisms to exploit sulfur reservoirs to ensure propagation within the host. Indeed, characterization of sulfur transporters has revealed that bacteria employ multiple tactics to acquire ideal sulfur sources, such as cysteine and its derivatives. However, bacteria that employ acquisition strategies targeting multiple sulfur sources complicate

Indexed as

CysteineSulfurBacteriaOxidation-ReductionRegulonCysteineSulfurcysteineglutathionenutrient acquisitionnutritional immunitysulfatesulfurγ-glutamyl transpeptidase

Identifiers

PMID35315692
PMCPMC9119060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.