ArticleJournal of public health research2022
18 months computed tomography follow-up after Covid-19 interstitial pneumonia.
Article in Journal of public health research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Clinical assessment of endothelial function in convalescent COVID-19 patients: a meta-analysis with meta-regressions.Annals of medicine · 2022Pooled it
- COVID-19's Radiologic, Functional, and Serologic Consequences at 6-Month and 18-Month Follow-up: A Prospective Cohort Study.Journal of Korean medical science · 2024Article
- Short- and Long-Term Chest-CT Findings after Recovery from COVID-19: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2024Review
- ERS International Congress 2023: highlights from the Thoracic Oncology Assembly.ERJ open research · 2024Article
- Quantitative CT at Follow-Up of COVID-19 Pneumonia: Relationship with Pulmonary Function Tests.Diagnostics (Basel, Switzerland) · 2023Article
- Idiopathic Pulmonary Fibrosis and Post-COVID-19 Lung Fibrosis: Links and Risks.Microorganisms · 2023Review
- Post-COVID-19 interstitial lung disease: Insights from a machine learning radiographic model.Frontiers in medicine · 2022Article
- Association between abnormalities on chest computed tomography and pulmonary function in patients with respiratory symptoms at 12 months after COVID-19.Radiologia brasileiraArticle
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aim is to evaluate the possible persistence of lung parenchyma alterations, in patients who have recovered from Covid-19. DESIGN AND
methodsWe enrolled a cohort of 115 patients affected by Covid-19, who performed a chest CT scan in the Emergency Department and a chest CT 18 months after hospital discharge. We performed a comparison between chest CT scan 18 months after discharge and spirometric data of patients enrolled. We obtained quantitative scores related to well-aerated parenchyma, interstitial lung disease and parenchymal consolidation. A radiologist recorded the characteristics indicated by the Fleischner Society and "fibrotic like" changes, expressed through a CT severity score ranging from 0 (no involvement) to 25 (maximum involvement).
results115 patients (78 men, 37 women; mean age 60.15 years old ±12.52). On quantitative analysis, after 18 months, the volume of normal ventilated parenchyma was significantly increased (16.34 points on average ±14.54, p<0.0001). Ground-glass opacities and consolidation values tend to decrease (-9.80 and -6.67 points, p<0.0001). On semiquantitative analysis, pneumonia extension, reactive lymph nodes and crazy paving reached statistical significance (p<0.0001). The severity score decreased by 2.77 points on average (SD 4.96; p<0.0001). There were not statistically significant changes on "fibrotic-like" changes correlated with level of treatment and there was not a statistically significant correlation between CT lung score and spirometric results obtained 18 months after discharge.
conclusionsPatients recovered from Covid-19 seem to have an improvement of ventilated parenchyma and "fibrotic-like" alterations. The level of treatment does not appear to influence fibrotic changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.