Evidence map›Paper›PMID 35315243›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Biomineralized Materials as Model Systems for Structural Composites: Intracrystalline Structural Features and Their Strengthening and Toughening Mechanisms.

Zhifei Deng, Zian Jia, Ling Li

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Guanine Crystal Formation at Physiological pH.Crystal growth & design · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Bio-Informed Porous Mineral-Based Composites.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  13. Review
  14. Review
  15. Article
  16. Biomineral-Based Composite Materials in Regenerative Medicine.International journal of molecular sciences · 2024
    Review
  17. Review
  18. Biomineralization and Properties of Guanine Crystals.Molecules (Basel, Switzerland) · 2023
    Review
  19. Article
  20. The Effect ofMaterials (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhifei DengDepartment of Mechanical Engineering, Virginia Polytechnic Institute of Technology and State University, Blacksburg, VA, 24060, USA.
Zian JiaDepartment of Mechanical Engineering, Virginia Polytechnic Institute of Technology and State University, Blacksburg, VA, 24060, USA.
Ling LiDepartment of Mechanical Engineering, Virginia Polytechnic Institute of Technology and State University, Blacksburg, VA, 24060, USA.ORCID 0000-0002-6741-9741

Funding

Air Force Office of Scientific Research FA9550-19-1-0033Air Force Office of Scientific Research FA9550-20-1-0161National Science Foundation CMMI-1825646National Science Foundation DMR-1942865US-Israel Binational Science Foundation BSF-2016341
6 · The paper itself

Abstract

Biomineralized composites, which are usually composed of microscopic mineral building blocks organized in 3D intercrystalline organic matrices, have evolved unique structural designs to fulfill mechanical and other biological functionalities. While it has been well recognized that the intricate architectural designs of biomineralized composites contribute to their remarkable mechanical performance, the structural features within and corresponding mechanical properties of individual mineral building blocks are often less appreciated in the context of bio-inspired structural composites. The mineral building blocks in biomineralized composites exhibit a variety of salient intracrystalline structural features, such as, organic inclusions, inorganic impurities (or trace elements), crystalline features (e.g., amorphous phases, single crystals, splitting crystals, polycrystals, and nanograins), residual stress/strain, and twinning, which significantly modify the mechanical properties of biogenic minerals. In this review, recent progress in elucidating the intracrystalline structural features of three most common biomineral systems (calcite, aragonite, and hydroxyapatite) and their corresponding mechanical significance are discussed. Future research directions and corresponding challenges are proposed and discussed, such as the advanced structural characterizations and formation mechanisms of intracrystalline structures in biominerals, amorphous biominerals, and bio-inspired synthesis.

Indexed as

Calcium CarbonateDurapatiteModels, BiologicalCalcium CarbonateDurapatitebiomineralscalcium carbonatehydroxyapatiteintracrystalline structuremechanical properties

Identifiers

PMID35315243
PMCPMC9108615

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.