Evidence map›Paper›PMID 35315236›Full record

ArticleMicrobial biotechnology2022

Peptide mediated, enhanced toxicity of a bacterial pesticidal protein against southern green stink bug.

Rahul Banerjee, Biviana Flores-Escobar, Nanasaheb P Chougule, Pablo Emiliano Cantón, Razvan Dumitru, Bryony C Bonning

Open access · goldAbstract read
In one paragraph

Article in Microbial biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Cry1Ba1-mediated toxicity of transgenicFrontiers in insect science · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rahul BanerjeeDepartment of Entomology and Nematology, University of Florida, PO Box 110620, Gainesville, FL, 32611, USA.
Biviana Flores-EscobarDepartment of Entomology and Nematology, University of Florida, PO Box 110620, Gainesville, FL, 32611, USA.
Nanasaheb P ChouguleInnovation Center, BASF Corporation, 3500 Paramount Parkway, Morrisville, NC, 27560, USA.
Pablo Emiliano CantónDepartment of Entomology and Nematology, University of Florida, PO Box 110620, Gainesville, FL, 32611, USA.
Razvan DumitruInnovation Center, BASF Corporation, 3500 Paramount Parkway, Morrisville, NC, 27560, USA.
Bryony C BonningDepartment of Entomology and Nematology, University of Florida, PO Box 110620, Gainesville, FL, 32611, USA.ORCID 0000-0002-9956-9613
University of Florida · USBASF (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The damage caused by stink bugs that feed on agricultural crops accounts for such significant losses that transgenic plant resistance to stink bugs would be highly desirable. As the level of toxicity of the Bacillus thuringiensis-derived, ETX/Mtx2 pesticidal protein Mpp83Aa1 is insufficient for practical use against the southern green stink bug Nezara viridula, we employed two disparate approaches to isolate peptides NvBP1 and ABP5 that bind to specific proteins (alpha amylase and aminopeptidase N respectively) on the surface of the N. viridula gut. Incorporation of these peptides into Mpp83Aa1 provided artificial anchors resulting in increased gut binding, and enhanced toxicity. These peptide-modified pesticidal proteins with increased toxicity provide a key advance for potential future use against N. viridula when delivered by transgenic plants to mitigate economic loss associated with this important pest.

Indexed as

HeteropteraPesticidesAnimalsBacterial ProteinsCrops, AgriculturalPeptidesBacterial ProteinsPeptidesPesticides

Identifiers

PMID35315236
PMCPMC9249324
OpenAlexW4220879988

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.