Evidence map›Paper›PMID 35314904›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2023

Impact of chronic kidney disease on in-hospital mortality and clinical outcomes of catheter ablation of ventricular tachycardia: Insights from the national readmission database.

Mahmoud Khalil, Ahmed Maraey, Amro Aglan, Emmanuel Akintoye, Mahmoud Salem, Ahmed M Elzanaty, Ahmed Younes, Ayman Saeyeldin, Chirag R Barbhaiya, Mohamed Shokr

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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Ventricular tachycardia in end-stage kidney disease.Proceedings (Baylor University. Medical Center) · 2025
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Mahmoud KhalilInternal Medicine Department Lincoln Medical and Mental Health Center, NY, New York, USA. mahmoudmagdy2188@gmail.com.ORCID http://orcid.org/0000-0003-0922-9672
Ahmed MaraeyDepartment of Internal Medicine, CHI St. Alexius Health/University of North Dakota, Bismarck, ND, USA.
Amro AglanDepartment of Internal Medicine, Lahey Hospital and Medical Center, Burlington, MA, USA.
Emmanuel AkintoyeDepartment of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.
Mahmoud SalemCenter for Advanced Heart and Lung Diseases, Baylor University Medical Center, TX, Dallas, USA.
Ahmed M ElzanatyCardiovascular Medicine Department, University of Toledo, Toledo, OH, USA.
Ahmed YounesInternal Medicine Department, East Carolina University, Greenville, NC, USA.
Ayman SaeyeldinInternal Medicine Department, Saint Mary Hospital, Waterbury, CT, USA.
Chirag R BarbhaiyaLeon H. Charney Division of Cardiology, Cardiac Electrophysiology, NYU Langone Health, New York University School of Medicine, New York City, NY, USA.
Mohamed ShokrLeon H. Charney Division of Cardiology, Cardiac Electrophysiology, NYU Langone Health, New York University School of Medicine, New York City, NY, USA.
New York University · USBaylor University Medical Center · USCleveland Clinic · USEast Carolina University · USLahey Hospital and Medical Center · USLincoln Medical Center · USSt Mary's Hospital · USUniversity of North Dakota · USUniversity of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation is an effective treatment for ventricular tachycardia (VT), albeit the decision to undergo this procedure is often influenced by underlying comorbidities. The present study aims at evaluating the effects of chronic kidney disease (CKD) on clinical outcomes of VT ablation.

methodsWe identified 7212 patients who presented between 2016 and 2018 and underwent catheter ablation for VT. Their clinical data were retrospectively accrued from the national readmission database (NRD) using the corresponding diagnosis codes. We compared clinical outcomes between patients with chronic kidney disease (CKD group) and patients without. Odds ratios (OR) for the primary and secondary outcomes were calculated, and multivariable regression analysis was utilized to adjust for confounding variables.

resultsCompared with patients without CKD, patients in CKD group were older (mean age 67.9 vs. 60.5 years, P < 0.01), had a longer mean length of stay (8.73 vs. 5.69 days, P < 0.01), and higher in-hospital mortality 113 (6.7%) vs. 119 (2.2%) (OR 2.24, 95% confidence interval (CI) (1.29-3.88), P < 0.01). CKD group patients had increased risk of developing acute kidney injury 726 (43%) vs. 623 (11.3%) (3.69 95% CI (2.87-4.74), P < 0.01).

conclusionIn patients with CKD, VT ablation is associated with worse clinical outcomes in-hospital mortality, acute kidney injury, mean length of stay, and total hospital charge. This significantly influences the decision-making prior to performing this procedure.

Indexed as

Catheter AblationTachycardia, VentricularAgedArrhythmias, CardiacHospital MortalityHumansPatient ReadmissionRetrospective StudiesTreatment OutcomeAblationChronic kidney diseaseNational readmission databaseVentricular tachycardia

Identifiers

PMID35314904
OpenAlexW4220731695

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.