Evidence map›Paper›PMID 35314638›Full record

ArticleTomography (Ann Arbor, Mich.)2022

Photon Counting CT and Radiomic Analysis Enables Differentiation of Tumors Based on Lymphocyte Burden.

Alex J Allphin, Yvonne M Mowery, Kyle J Lafata, Darin P Clark, Alex M Bassil, Rico Castillo, Diana Odhiambo, Matthew D Holbrook, Ketan B Ghaghada, Cristian T Badea

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  6. Prognostic value of different discretization parameters inJournal of medical imaging (Bellingham, Wash.) · 2024
    Article
  7. Review
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  9. Imaging in translational cancer research.Cancer biology & medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alex J AllphinQuantitative Imaging and Analysis Lab, Department of Radiology, Duke University Medical Center, Durham, NC 277101, USA.
Yvonne M MoweryDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0002-9839-2414
Kyle J LafataDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Darin P ClarkQuantitative Imaging and Analysis Lab, Department of Radiology, Duke University Medical Center, Durham, NC 277101, USA.
Alex M BassilDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Rico CastilloDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Diana OdhiamboDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Matthew D HolbrookQuantitative Imaging and Analysis Lab, Department of Radiology, Duke University Medical Center, Durham, NC 277101, USA.
Ketan B GhaghadaE.B. Singleton Department of Radiology, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0003-1012-8668
Cristian T BadeaQuantitative Imaging and Analysis Lab, Department of Radiology, Duke University Medical Center, Durham, NC 277101, USA.
Duke University · USDuke Medical Center · USBaylor College of Medicine · US

Funding

Targeting the immunosuppressive tumor microenvironment to enhance efficacy of radiotherapy and immuno-radiotherapy for oral cancerU01DE028233 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ANNAPRAGADA, ANANTH V, SIKORA, ANDREW · 2018 to 2022
$3.9M
The Duke Preclinical Research Resources for Quantitative Imaging BiomarkersU24CA220245 · NCI · DUKE UNIVERSITY · PI BADEA, CRISTIAN T · 2017 to 2021
$2.8M
Cardiac photon counting CT and its application in studying interactions between Alzheimer's and heart diseaseRF1AG070149 · NIA · DUKE UNIVERSITY · PI BADEA, CRISTIAN T · 2021 to 2022
$2.1M
Employing Novel Primary Mouse Models of Head and Neck Cancer to Overcome Chemoradiation ResistanceK08DE029887 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOWERY, YVONNE MARIE · 2020 to 2024
$804k
NCI NIH HHS U24 CA220245NIA NIH HHS RF1 AG070149NIDCR NIH HHS K08 DE029887NIDCR NIH HHS U01 DE028233
6 · The paper itself

Abstract

The purpose of this study was to investigate if radiomic analysis based on spectral micro-CT with nanoparticle contrast-enhancement can differentiate tumors based on lymphocyte burden. High mutational load transplant soft tissue sarcomas were initiated in

Indexed as

Contrast MediaSarcomaAnimalsLymphocytesMicePhantoms, ImagingX-Ray MicrotomographyContrast Mediamicro-CTnanoparticlesphoton counting detectorpreclinicalradiogenomicsradiomicsspectral CT

Identifiers

PMID35314638
PMCPMC8938796
OpenAlexW4220700021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.