Evidence map›Paper›PMID 35314481›Full record

Trial reportClinical journal of the American Society of Nephrology : CJASN2022

Multifaceted Intervention to Increase the Use of Home Dialysis: A Cluster Randomized Controlled Trial.

Braden J Manns, Amit X Garg, Manish M Sood, Thomas Ferguson, S Joseph Kim, David Naimark, Gihad E Nesrallah, Steven D Soroka, Monica Beaulieu, Stephanie N Dixon and 3 more

3 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical journal of the American Society of Nephrology : CJASN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02183987 nacompletednot on this map

Knowledge Translation Interventions to Prevent the Early Initiation of Dialysis: A Cluster Randomized Trial

TypeinterventionalSponsorUniversity of ManitobaRan2014 to 2016Enrolled55ConditionsChronic Kidney DiseaseArmsActive Knowledge Translation Intervention
NCT02202018 nacompletednot on this map

Patient and Provider Education for Patients With Severe Chronic Kidney Disease: Assessing the Impact on Barriers and Use of Home Dialysis

TypeinterventionalSponsorUniversity of CalgaryRan2014 to 2018Enrolled55ConditionsChronic Kidney DiseaseArmsActive KT intervention
NCT06925776 narecruitingnot on this mapstarted 2025, after this paper: background citation

Community Health Workers in an Interdisciplinary Outpatient CKD Clinic to Optimize Social Care Navigation, Patient Engagement, and Home Dialysis Utilization- the CHOOSE Home Trial

TypeinterventionalSponsorMontefiore Medical CenterRan2025 to 2028Enrolled106ConditionsKidney Replacement TherapyArmsCHOOSE Home Intervention, Usual Care
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. How to Leverage Implementation Science to Achieve Equity in Nephrology Care Delivery.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025
    Article
  3. Article
  4. Article
  5. Identifying Major Barriers to Home Dialysis (The IM-HOME Study): Findings From a National Survey of Patients, Care Partners, and Providers.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Article
  6. Review
  7. Is There an Ideal Recipe to Increase Home Dialysis Use? Is It Enough?Clinical journal of the American Society of Nephrology : CJASN · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 1 country.

Braden J MannsDepartment of Medicine and Community Health Sciences, Libin Cardiovascular Institute and O'Brien Public Health Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada braden.manns@albertahealthservices.ca.
Amit X GargDivision of Nephrology, Department of Medicine, Western University, London, Ontario, Canada.
Manish M SoodThe Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0002-9146-2344
Thomas FergusonDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
S Joseph KimInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
David NaimarkDivision of Nephrology, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario, Canada.ORCID 0000-0002-0621-0637
Gihad E NesrallahLi Ka Shing Knowledge Institute, Keenan Research Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Steven D SorokaDepartment of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Monica BeaulieuDivision of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada.
Stephanie N DixonInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Ahsan AlamDivision of Nephrology, McGill University Health Centre, Montreal, Quebec, Canada.
Selina AlluDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Navdeep TangriDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Western University · CADalhousie University · CALibin Cardiovascular Institute of Alberta · CAMcGill University Health Centre · CASeven Oaks General Hospital · CASt. Michael's Hospital · CASunnybrook Health Science Centre · CAUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Manitoba · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

CIHR
6 · The paper itself

Abstract

BACKGROUND AND

objectivesHome dialysis therapies (peritoneal and home hemodialysis) are less expensive and provide similar outcomes to in-center hemodialysis, but they are underutilized in most health systems. Given this, we designed a multifaceted intervention to increase the use of home dialysis. In this study, our objective was to evaluate the effect of this intervention on home dialysis use in CKD clinics across Canada. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a cluster randomized controlled trial in 55 CKD clinic clusters in nine provinces in Canada between October 2014 and November 2015. Participants included all adult patients who initiated dialysis in the year following the intervention. We evaluated the implementation of a four-component intervention, which included phone surveys from a knowledge translation broker, a 1-year center-specific audit/feedback on home dialysis use, delivery of an educational package (including tools aimed at both providers and patients), and an academic detailing visit. The primary outcome was the proportion of patients using home dialysis at 180 days after dialysis initiation.

resultsA total of 55 clinics were randomized (27 in the intervention and 28 in the control), with 5312 patients initiating dialysis in the 1-year follow-up period. In the primary analysis, there was no difference in the use of home dialysis at 180 days in the intervention and control clusters (absolute risk difference, 4%; 95% confidence interval, -2% to 10%). Using a difference-in-difference comparison, the use of home dialysis at 180 days was similar before and after implementation of the intervention (difference of 0% in intervention clinics; 95% confidence interval, -2% to 3%; difference of 0.8% in control clinics; 95% confidence interval, -1% to 3%;

conclusionsA multifaceted intervention did not increase the use of home dialysis in adults initiating dialysis. CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER: A Cluster Randomized Trial to Assess the Impact of Patient and Provider Education on Use of Home Dialysis, NCT02202018.

Indexed as

Hemodialysis, HomeRenal Insufficiency, ChronicAdultCanadaHumansRenal DialysisSurveys and Questionnairesdialysisend stage kidney diseasehome hemodialysisperitoneal dialysisrandomized controlled trials

Identifiers

PMID35314481
PMCPMC8993468
OpenAlexW4220881608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.