Evidence map›Paper›PMID 35314475›Full record

ArticleBMJ open2022

Prevalence and risk factors associated with chronic kidney disease in Nepal: evidence from a nationally representative population-based cross-sectional study.

Anil Poudyal, Khem Bahadur Karki, Namuna Shrestha, Krishna Kumar Aryal, Namra Kumar Mahato, Bihungum Bista, Laxmi Ghimire, Dirghayu Kc, Pradip Gyanwali, Anjani Kumar Jha and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07506980 (Effect of Nurse-led Intervention on Self-care Adherence and Quality of Life Among Patients Undergoing Hemodialysis.), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07506980 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Nurse-led Intervention on Self-care Adherence and Quality of Life Among Patients Undergoing Hemodialysis.

TypeinterventionalSponsorKathmandu University School of Medical SciencesRan2026 to 2026Enrolled112ConditionsNurse Led Interventions, Patients on Hemodialysis, Self Care, Quality of LifeArmslaptop based education and counselling, Reminder call, distribution of self care booklet having all the content covered in discussion
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Global health inequalities of chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Anil Poudyal *Research section, Nepal Health Research Council, Ramshah path, Kathmandu, Nepal poudyalanil123@gmail.com meghdhimal@gmail.com.ORCID 0000-0003-2687-2993
Khem Bahadur Karki *Institute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Namuna ShresthaPublic Health Promotion and Development Organization, Kathmandu, Nepal.ORCID 0000-0003-2697-5976
Krishna Kumar AryalPublic Health Promotion and Development Organization, Kathmandu, Nepal.
Namra Kumar MahatoResearch section, Nepal Health Research Council, Ramshah path, Kathmandu, Nepal.
Bihungum BistaResearch section, Nepal Health Research Council, Ramshah path, Kathmandu, Nepal.
Laxmi GhimireSanjeevani College of Medical Sciences, Rupandehi, Nepal.
Dirghayu KcPublic Health Promotion and Development Organization, Kathmandu, Nepal.ORCID 0000-0002-6184-0615
Pradip GyanwaliResearch section, Nepal Health Research Council, Ramshah path, Kathmandu, Nepal.
Anjani Kumar JhaResearch section, Nepal Health Research Council, Ramshah path, Kathmandu, Nepal.
Vanessa Garcia-LarsenDepartment of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Ulrich KuchInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
David A GronebergInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Sanjib Kumar SharmaDepartment of Internal Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal.ORCID 0000-0002-8392-8028
Meghnath DhimalResearch section, Nepal Health Research Council, Ramshah path, Kathmandu, Nepal poudyalanil123@gmail.com meghdhimal@gmail.com.ORCID 0000-0001-7176-7821
Nepal Health Research Council · NPGoethe University Frankfurt · DEB.P. Koirala Institute of Health Sciences · NPCollege of Medical Sciences · NPJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to determine population-based prevalence of chronic kidney disease (CKD) and its associated factors in Nepal. STUDY

designThe study was a nationwide population-based cross-sectional study. SETTING AND

participantsCross-sectional survey conducted in a nationally representative sample of 12 109 Nepalese adult from 2016 to 2018 on selected chronic non-communicable diseases was examined. Multistage cluster sampling with a mix of probability proportionate to size and systematic random sampling was used for the selection of individuals aged 20 years and above. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome in this study was population-based prevalence of CKD in Nepal. A participant was considered to have CKD if the urine albumin-to-creatinine ratio was greater than or equal to 30 mg/g and/or estimated glomerular filtration rate is less than 60 mL/min/1.73 m

resultsThe overall prevalence of CKD in Nepal was 6.0% (95% CI 5.5 to 6.6). Factors independently associated with CKD included older age (adjusted OR (AOR) 2.6, 95% CI 1.9 to 3.6), Dalit caste (AOR 1.6, 95% CI 1.1 to 2.3), hypertension (AOR 2.4, 95% CI 2.0 to 3.0), diabetes mellitus (AOR 3.2, 95% CI 2.5 to 4.1), raised total cholesterol (AOR 1.3, 95% CI 1.0 to 1.6) and increased waist-to-hip ratio (AOR 1.6, 95% CI 1.2 to 2.3).

conclusionThis nationally representative study shows that the prevalence of CKD in the adult population of Nepal is substantial, and it is independently associated with several cardiometabolic traits. These findings warrant longitudinal studies to identify the causes of CKD in Nepal and effective strategies to prevent it.

Indexed as

Renal Insufficiency, ChronicAdultCross-Sectional StudiesGlomerular Filtration RateHumansNepalPrevalenceRisk Factorschronic renal failuredialysisglomerulonephritisrenal transplantation

Identifiers

PMID35314475
PMCPMC8938697
OpenAlexW4220745563

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.