Evidence map›Paper›PMID 35314143›Full record

ArticleBiophysical journal2022

Inertial artifact in viscoelastic measurements of striated muscle: Modeling and experimental results.

Mark S Miller, Chad R Straight, Bradley M Palmer

Open access · greenAbstract read
In one paragraph

Article in Biophysical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mark S MillerDepartment of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts.
Chad R StraightDepartment of Kinesiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts.
Bradley M PalmerDepartment of Molecular Physiology and Biophysics, Larner College of Medicine, University of Vermont, Burlington, Vermont. Electronic address: bmpalmer@uvm.edu.
University of Massachusetts Amherst · USUniversity of Vermont · US

Funding

High Throughput Screening of Pharmaceuticals Targeting Heart Cell Contractile FunctionR44HL137603 · NHLBI · IONOPTIX, LLC · PI PALMER, BRADLEY M · 2019 to 2020
$1.5M
NHLBI NIH HHS R44 HL137603
6 · The paper itself

Abstract

Viscoelastic properties of striated muscle are often measured using length perturbation analysis and quantified as a complex modulus, whose elastic and viscous components reflect the energy-storage and energy-absorbing properties of the tissue, respectively. The energy stored as inertia is commonly ignored due to the small size of samples examined, typically <1 mm. Considering recent advances in tissue engineering to generate muscle tissues of larger sizes, we questioned whether ignoring the inertial artifact was still reasonable in these samples. To answer this question, we derived and solved the one-dimensional wave equation that describes the propagation of strain along the length of a sample. The inertial artifact was predicted to contaminate the elastic modulus with (2πf)

Indexed as

ArtifactsMuscle, SkeletalAnimalsElasticityElastic ModulusMammalsMiceRatsViscosity

Identifiers

PMID35314143
PMCPMC9072571
OpenAlexW4221051326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.