Evidence map›Paper›PMID 35314025›Full record

ArticleDeutsches Arzteblatt international2022

ST-Elevation Myocardial Infarction as a First Event.

Alicia Jeanette Fischer, Jannik Feld, Lena Makowski, Christiane Engelbertz, Leonie Kühnemund, Christian Günster, Patrik Dröge, Thomas Ruhnke, Joachim Gerß, Eva Freisinger and 2 more

Open access · greenAbstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alicia Jeanette FischerDepartment of Cardiology III: Congenital Heart Defects and Valvular Heart Disease, University Hospital Münster; Institute for Biostatistics and Clinical Research, University of Münster; Department of Cardiology I: Coronary Heart Disease, Heart Failure, and Angiology, University Hospital Münster; Research Institute of the AOK (WIdO), Berlin.
Jannik Feld
Lena Makowski
Christiane Engelbertz
Leonie Kühnemund
Christian Günster
Patrik Dröge
Thomas Ruhnke
Joachim Gerß
Eva Freisinger
Holger Reinecke
Jeanette Köppe
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurvival after ST-elevation myocardial infarction (STEMI) as a first event in Germany was analyzed.

methodsAdults with a first-event STEMI were included for analysis on the basis of insurance data from a German health insurance provider (AOK; approximately 26 million members; median follow-up 48.5 months). The primary endpoints were 30-day mortality, reinfarction or death, major adverse cardiovascular and cerebro - vascular events (MACCE), long-term survival for more than 90 days, and overall survival (OS).

resultsSTEMI occurred in 17 444 patients (32.8% women). The women were older than the men (median age 74 versus 60 years) and suffered more frequently from cardiovascular comorbidities such as diabetes mellitus, chronic renal disease, and arterial hypertension. Women underwent endovascular or surgical treatment less frequently, but sustained complications (cardiogenic shock, resuscitation) more frequently. After adjustment of the data, women were at higher risk of 30-day mortality (odds ratio [OR] 1.17, 95% confidence interval [95% CI] [1.07; 1.28]), reinfarction or death (hazard ratio [HR] 1.09, 95% CI [1.04; 1.16]), MACCE (HR 1.09, 95% CI [1.04; 1.15]), and poorer OS (HR 1.10, 95% CI [1.04; 1.17]). This effect was especially pronounced in women aged ≤ 60 years. No differences between the sexes were seen among patients who survived for 90 days after the infarction.

conclusionIn Germany, women ≤ 60 years display a higher 30-day mortality after first-event STEMI, which affects their overall survival. Younger women should receive intensified medical attention after STEMI, especially in the early phase.

Indexed as

Percutaneous Coronary InterventionST Elevation Myocardial InfarctionAdultAgedFemaleHospital MortalityHumansMaleProportional Hazards ModelsRisk FactorsTime FactorsTreatment Outcome

Identifiers

PMID35314025
PMCPMC9437838
OpenAlexW4221005187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.