ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2022
A Comparison of Blood Collection Techniques in Mice and their Effects on Welfare.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Aquatic Advancements: Refining and Validating a Zebrafish Survival Blood Collection Technique.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- A novel blood collection technique from the rat thoracic aorta: employing a diaphragm sac as a reservoir.Laboratory animal research · 2026Article
- Comparative Analysis of Cardiac Puncture and Perfusate Blood Collection for Murine Extracellular Vesicle Isolation.Methods and protocols · 2026Article
- CREATINE KINASE IS ELEVATED BY THE SUBMANDIBULAR VEIN BLEED TECHNIQUE, OBSCURING THE MEASUREMENT OF MUSCLE DAMAGE IN SEPSIS.Shock (Augusta, Ga.) · 2025Article
- Perspectives of FTIR as Promising Tool for Pathogen Diagnosis, Sanitary and Welfare Monitoring in Animal Experimentation Models: A Review Based on Pertinent Literature.Microorganisms · 2024Review
- Acclimation and Blood Sampling: Effects on Stress Markers in C57Bl/6J Mice.Animals : an open access journal from MDPI · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple methods are used to collect blood from mice; these methods have different effects on animal welfare. This study compared blood collection from facial, chin, and saphenous locations with regard to various parameters, including the time needed to collect blood, the number of attempts needed, success at completing the blood collection, volume of blood loss, weight changes in the mouse, presence of external lesions after blood collection and gross lesions at necropsy, physical signs during blood collection (vocalization, urination, and defecation), fecal corticosterone after blood collection, and blood chemistry values. While no one technique was clearly better for animal welfare, each technique had benefits and drawbacks.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.