ArticleBMC pulmonary medicine2022
A comparative analysis of lung function and spirometry parameters in genotype-controlled natives living at low and high altitude.
Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Development of the Respiratory System During Adolescence.Advances in experimental medicine and biology · 2026Review
- Association Between Pulmonary Function Parameters and Apnea Hypopnea Index in Asthmatic Children Living at High Altitude.Canadian respiratory journal · 2026Article
- Comparative analysis of pulmonary function in diverse ethnic adults living at low and high altitudes.Respiratory research · 2025Observational
- Detrimental Effects of Hypoxia on Cognitive Function: Adaptations, Challenges, and Resilience in Andean Populations.Journal of racial and ethnic health disparities · 2025Article
- Exploring the genetic footprints of high altitude adapted humans and livestock.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Review
- The prevalence of chronic obstructive pulmonary disease in high-altitude areas of China: a systematic review and meta-analysis.Journal of thoracic disease · 2025Article
- Forced vital capacity of healthy Iranian adults in Tehran.BMC pulmonary medicine · 2025Article
- DNA methylation in adaptation to high-altitude environments and pathogenesis of related diseases.Human genomics · 2025Review
- Adjustment Criteria for Air-Quality Standards by Altitude: A Scoping Review with Regulatory Overview.International journal of environmental research and public health · 2025Article
- Prevalence of chronic obstructive pulmonary disease in high-risk populations at low, intermediate, high altitudes: a population based cross-sectional study in Yunnan Province, China.BMC pulmonary medicine · 2025Article
- Prevalence and Risk Factors of Spirometry-Defined Small Airway Dysfunction in the High-Risk Population for COPD in Yunnan Province, China: A Population Based Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Ecuador genetic mosaic: biological and adaptive variations across Mestizos, Native Amerindians, and Afro-Ecuadorians. Implications for public health and precision medicine.Frontiers in genetics · 2025Review
- Impact of Low Altitude-Hilly Terrain on Pulmonary Health in Young Adults: A Gender-Based Spirometric Analysis.Journal of pharmacy & bioallied sciences · 2024Article
- Factors related with lung functions among Orang Asli in Tasik Chini, Malaysia: a cross-sectional study.BMC public health · 2024Article
- Work at high altitude and non-fatal cardiovascular disease associated with unfitness to work: Prospective cohort observation.PloS one · 2024Article
- Editorial: Integrative physiological approaches to understand high altitude adaptation.Frontiers in physiology · 2024Article
- The associations between body composition and vital capacity index of medical students in Shenyang of China: a cross-sectional survey.BMC pulmonary medicine · 2022Article
- SARS-CoV-2 Viral Load Analysis at Low and High Altitude: A Case Study from Ecuador.International journal of environmental research and public health · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe reference values for lung function are associated to anatomical and lung morphology parameters, but anthropometry it is not the only influencing factor: altitude and genetics are two important agents affecting respiratory physiology. Altitude and its influence on respiratory function has been studied independently of genetics, considering early and long-term acclimatization.
objectiveThe objective of this study is to evaluate lung function through a spirometry study in autochthonous Kichwas permanently living at low and high-altitude. METHODOLOGY: A cross-sectional study of spirometry differences between genetically matched lowland Kichwas from Limoncocha (230 m) at Amazonian basin and high-altitude Kichwas from Oyacachi (3180 m) in Andean highlands. The sample size estimates permitted to recruited 118 patients (40 men and 78 women) from Limoncocha and 95 (39 men and 56 women) from Oyacachi. Chi-square method was used to analyze association or independence of categorical variables, while Student's t test was applied to comparison of means within quantitative variables. ANOVA, or in the case that the variables didn't meet the criteria of normality, Kruskal Wallis test were used to compare more than two groups.
resultsThe FVC and the FEV
conclusionResidents of Oyacachi had greater FVC and FEV
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