ReviewJournal of clinical tuberculosis and other mycobacterial diseases2022
Undernutrition is feeding the tuberculosis pandemic: A perspective.
Review in Journal of clinical tuberculosis and other mycobacterial diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 63 citations in OpenAlex.
- Can Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis be Treated More Successfully?Public health challenges · 2026Article
- Survival and risk factors of mortality among patients with TB/HIV coinfection in Kigali City, Rwanda: a retrospective cohort study (2019-2024).BMC infectious diseases · 2026Article
- Infection with Mycobacterium tuberculosis depletes host fatty acids in humans and non-human primates.EBioMedicine · 2026Article
- Diet and nutrition status of adult multidrug-resistant tuberculosis cases, household controls, and community controls in Mumbai, India.PLOS global public health · 2026Article
- Tuberculosis in Tibetan refugee settlements in India: a human rights perspective.Frontiers in public health · 2026Article
- Modelling tuberculosis transmission dynamics in Malaysia.Frontiers in public health · 2026Article
- Magnitude of undernutrition and associated factors among adult tuberculosis patients in West Shoa Zone, Oromia Region, Ethiopia: a facility-based cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Weight gain during tuberculosis treatment increases the risk of post-tuberculosis metabolic syndrome.medRxiv : the preprint server for health sciences · 2025Article
- Under-nutrition among adult tuberculosis patients completing intensive-phase treatment at public health facilities in Kembata Zone, Central Ethiopia Region.BMC infectious diseases · 2025Article
- Body Size and Risk of Death During the 1918 Influenza Pandemic in Alaska.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Unraveling the Drivers of Tuberculosis: A Retrospective Panel Data Study Across 70 Developing Countries.Health science reports · 2025Article
- Assessment of the Syndemic Relationship Between Individual, Social, and Structural Determinants of Tuberculosis Among People Living in Johannesburg, South Africa.International journal of environmental research and public health · 2025Article
- Impact of Nutritional Counselling and Support on Body Mass Index Recovery and Treatment Outcomes Among Tuberculosis Patients in the Lao People's Democratic Republic.Tropical medicine and infectious disease · 2025Article
- Modelling the effect of a nutritional shock on tuberculosis in India.BMC global and public health · 2025Article
- Impact of premorbid nutritional status on TB severity.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2025Article
- Incidence and risk factors for tuberculosis at a rural HIV clinic in Uganda, 2012-2019; A retrospective cohort study.BMC public health · 2025Article
- Clinical characteristics and risk factors analysis of bilateral renal tuberculosis.International urology and nephrology · 2025Article
- Anthropometric growth trajectories of children presenting with presumptive pulmonary TB.IJTLD open · 2025Article
- Outcomes of Treating Tuberculosis Patients with Drug-Resistant Tuberculosis, Human Immunodeficiency Virus, and Nutritional Status: The Combined Impact of Triple Challenges in Rural Eastern Cape.International journal of environmental research and public health · 2025Article
- Impact of Severity of COVID-19 in TB Disease Patients: Experience from an Italian Infectious Disease Referral Hospital.Infectious disease reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis (TB) is a major cause of death worldwide, with 1.5 million deaths in 2020. While TB incidence and mortality had previously been on a downwards trend, in 2020, TB mortality actually rose for the first time in a decade, largely due to the COVID-19 pandemic. Undernutrition is the leading risk factor for TB, with a population attributable fraction (PAF) of 15%, compared to 7.6% for HIV. Individuals who are undernourished are more likely to develop active TB compared to those with a healthy bodyweight. They are also more likely to have greater severity of TB, and less likely to have successful TB treatment outcomes. The likelihood of TB mortality significantly increases as weight decreases. Nutritional interventions are likely to improve both nutritional status and TB treatment success, thereby decreasing TB mortality. However, many previous studies focusing on nutritional interventions have provided insufficient calories or been underpowered. Nutritional supplementation will be particularly important as factors such as the COVID-19 pandemic, climate change, and political conflict further threaten food security. The global TB elimination effort can no longer afford to ignore undernutrition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.