Evidence map›Paper›PMID 35313693›Full record

ArticleiScience2022

Microbiome-by-ethanol interactions impact Drosophila melanogaster fitness, physiology, and behavior.

James Angus Chandler, Lina Victoria Innocent, Daniel Jonathan Martinez, Isaac Li Huang, Jane Lani Yang, Michael Bruce Eisen, William Basil Ludington

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. The importance of host physical niches for the stability of gut microbiome composition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  4. Cellular and molecular organization of the Drosophila foregut.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Applied and environmental microbiology · 2023
    Article
  6. Review
  7. Honeybees show an increased preference for dietary alcohol when parasitized.Behavioral ecology : official journal of the International Society for Behavioral Ecology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

James Angus ChandlerDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Lina Victoria InnocentDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Daniel Jonathan MartinezDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA.
Isaac Li HuangDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Jane Lani YangDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Michael Bruce EisenDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
William Basil LudingtonDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
University of California, Berkeley · USCarnegie Institution for Science · USHoward Hughes Medical Institute · USJohns Hopkins University · US

Funding

Developing a reduced complexity model gut microbiome in the behavior model, Drosophila melanogasterDP5OD017851 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI LUDINGTON, WILLIAM BASIL · 2013 to 2017
$2.0M
Microbially-mediated ethanol resistance in Drosophila: host benefits and potential mechanismsF32AA024376 · NIAAA · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHANDLER, JAMES · 2015 to 2017
$173k
NIAAA NIH HHS F32 AA024376NIH HHS DP5 OD017851
6 · The paper itself

Abstract

The gut microbiota can affect how animals respond to ingested toxins, such as ethanol, which is prevalent in the diets of diverse animals and often leads to negative health outcomes in humans. Ethanol is a complex dietary factor because it acts as a toxin, behavioral manipulator, and nutritional source, with both direct effects on the host as well as indirect ones through the microbiome. Here, we developed a model for chronic, non-intoxicating ethanol ingestion in the adult fruit fly,

Indexed as

Biological sciencesGeneticsMicrobiologyMicrobiomeMolecular biologyPhysiology

Identifiers

PMID35313693
PMCPMC8933687
OpenAlexW4214534523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.