Evidence map›Paper›PMID 35313689›Full record

ArticleiScience2022

Intracellular metabolic adaptation of intraepithelial CD4

Yosuke Harada, Tomohisa Sujino, Kentaro Miyamoto, Ena Nomura, Yusuke Yoshimatsu, Shun Tanemoto, Satoko Umeda, Keiko Ono, Yohei Mikami, Nobuhiro Nakamoto and 7 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Improve your success with fish cell lines-small things that matter.In vitro cellular & developmental biology. Animal · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Pathways and mechanisms of CD4Trends in immunology · 2024
    Review
  7. Article
  8. Legend or Truth: Mature CD4Biomedicines · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Development and function of natural TCRFrontiers in immunology · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Yosuke HaradaDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Tomohisa SujinoCenter for Diagnostic and Therapeutic Endoscopy, Keio University Hospital, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Kentaro MiyamotoDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Ena NomuraDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Yusuke YoshimatsuDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Shun TanemotoDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Satoko UmedaDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Keiko OnoDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Yohei MikamiDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Nobuhiro NakamotoDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Kaoru TakabayashiCenter for Diagnostic and Therapeutic Endoscopy, Keio University Hospital, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Naoki HosoeCenter for Diagnostic and Therapeutic Endoscopy, Keio University Hospital, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Haruhiko OgataCenter for Diagnostic and Therapeutic Endoscopy, Keio University Hospital, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Tuneo IkenoueDivision of Clinical Genome Research, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Atsushi HiraoDivision of Molecular Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Yoshiaki KubotaDepartment of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan.
Takanori KanaiDepartment of Gastroenterology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Keio University Hospital · JPKanazawa University · JPKeio University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal intraepithelial lymphocytes (IELs), the first line of defense against microbial and dietary antigens, are classified as natural or induced based on their origin and receptor expression. Induced CD4

Indexed as

Biological sciencesCell biologyComponents of the immune systemImmunology

Identifiers

PMID35313689
PMCPMC8933710
OpenAlexW4214843117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.