Evidence map›Paper›PMID 35313326›Full record

ReviewMedical science monitor : international medical journal of experimental and clinical research2022

A Review of Recent Studies on the Effects of SARS-CoV-2 Infection and SARS-CoV-2 Vaccines on Male Reproductive Health.

Leila Adamyan, Vladimir Elagin, Valeriy Vechorko, Assia Stepanian, Anton Dashko, Dmitriy Doroshenko, Yana Aznaurova, Maxim Sorokin, Andrew Garazha, Anton Buzdin

Open access · hybridAbstract readReview
In one paragraph

Review in Medical science monitor : international medical journal of experimental and clinical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Leila AdamyanDepartment of Reproductive Medicine and Surgery, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation.
Vladimir ElaginDepartment of Reproductive Medicine and Surgery, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation.
Valeriy VechorkoO.M. Filatov City Clinical Hospital No.15, Moscow, Russian Federation.
Assia StepanianAcademia of Women's Health and Endoscopic Surgery, Atlanta, GA, USA.
Anton DashkoO.M. Filatov City Clinical Hospital No.15, Moscow, Russian Federation.
Dmitriy DoroshenkoO.M. Filatov City Clinical Hospital No.15, Moscow, Russian Federation.
Yana AznaurovaDepartment of Reproductive Medicine and Surgery, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation.
Maxim SorokinMoscow Institute of Physics and Technology (National Research University), Dolgoprudnyj, Moscow region, Russian Federation.
Andrew GarazhaOmicsWay Corp., Walnut, CA, USA.
Anton BuzdinMoscow Institute of Physics and Technology (National Research University), Dolgoprudnyj, Moscow region, Russian Federation.
City Clinical Hospital No15 named. O. M. Filatova · RUMoscow State University of Medicine and Dentistry · RUMoscow Institute of Physics and Technology · RUReal Academia Española · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to world statistics, men are more susceptible to the coronavirus disease 2019 (COVID-19) than are women. Considering the interconnection between infections and male infertility, investigation of the potential impact of COVID-19 on men's reproductive health is now a particularly relevant topic. Published data indicate decreased sperm quality and orchitis development in patients with COVID-19, including reduced sperm count, decreased sperm motility, and elevated DNA fragmentation index. Although mass vaccination against COVID-19 is currently being carried out worldwide using available authorized vaccines, the effect of these vaccines on men's reproductive health has not yet been investigated. There is currently no evidence that SARS-CoV-2 can be transmitted in semen, but available data suggest that it can infect spermatogonia, spermatids, Leydig cells, and Sertoli cells. Therefore, SARS-CoV-2 orchitis and reduced male fertility may be long-term complications of COVID-19, which requires further investigation. Currently, there is also no evidence that vaccines against SARS-CoV-2 have any pathological effects on spermatogenesis or male reproductive health. Thus, further studies are needed to determine the effects of COVID-19 and COVID-19 vaccines on men's reproductive health, which will help to optimize the management and rehabilitation of these patients. This review aims to discuss recent studies on the impact of the COVID-19 and COVID-19 vaccines on men's reproductive health. The article addresses various issues such as the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on testosterone biosynthesis, semen parameters, testicular tissue, and epididymis.

Indexed as

COVID-19COVID-19 VaccinesHumansMaleReproductive HealthSARS-CoV-2Sperm MotilityViral VaccinesCOVID-19 VaccinesViral Vaccines

Identifiers

PMID35313326
PMCPMC8951594
OpenAlexW4213179338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.