Evidence map›Paper›PMID 35313127›Full record

ArticleChild abuse & neglect2022

The mediating role of attachment and mentalising in the relationship between childhood maltreatment, self-harm and suicidality.

Maria Stagaki, Tobias Nolte, Janet Feigenbaum, Brooks King-Casas, Terry Lohrenz, Peter Fonagy, Personality and Mood Disorder Research Consortium, P Read Montague

Registry-linked trialAbstract read
In one paragraph

Article in Child abuse & neglect, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05613972 (Using Integrated Suicide and Trauma Therapy to Reduce Suicide Risk Among Adults With a History of Childhood Trauma), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05613972 narecruitingnot on this mapstarted 2025, after this paper: background citation

Using Integrated Suicide and Trauma Therapy to Reduce Suicide Risk Among Adults With a History of Childhood Trauma

TypeinterventionalSponsorUnity Health TorontoRan2025 to 2027Enrolled20ConditionsSuicide, Trauma, Major Depressive DisorderArmsIntegrated Suicide and Trauma Therapy
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Theory of Mind and Suicidality: A Meta-Analysis.Archives of suicide research : official journal of the International Academy for Suicide Research
    Pooled it
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  3. Childhood Trauma and Aggression: The Role of Epistemic Trust.Journal of child & adolescent trauma · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria StagakiDivision of Psychiatry, University College London, London, United Kingdom. Electronic address: maria.stagaki.19@ucl.ac.uk.
Tobias NolteWellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom; Anna Freud National Centre for Children and Families, London, United Kingdom.
Janet FeigenbaumResearch Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.
Brooks King-CasasFralin Biomedical Research Institute, Department of Psychology, Virginia Tech, Roanoke, VA, United States of America.
Terry LohrenzFralin Biomedical Research Institute, Department of Psychology, Virginia Tech, Roanoke, VA, United States of America.
Peter FonagyAnna Freud National Centre for Children and Families, London, United Kingdom; Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.
Personality and Mood Disorder Research Consortium
P Read MontagueWellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom; Fralin Biomedical Research Institute, Department of Psychology, Virginia Tech, Roanoke, VA, United States of America; Department of Physics, Virginia Tech, Blacksburg, VA, United States of America; Department of Psychiatry and Behavioral Medicine, Virginia Tech Carilion School of Medicine, Virginia Tech, Roanoke, VA, United States of America.

Funding

Neurobehavioral Mechanisms of Social Dysfunction in Borderline Personality DisorderR01MH115221 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASAS, BROOKS · 2018 to 2022
$3.3M
Dopaminergic encoding of counterfactual information in human striatumR01NS092701 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MONTAGUE, P READ · 2015 to 2019
$2.6M
Department of Health NF-SI-0514-10157NIMH NIH HHS R01 MH115221NINDS NIH HHS R01 NS092701Wellcome Trust
6 · The paper itself

Abstract

backgroundAlthough the relationship between childhood maltreatment, self-harm and suicidality is well-established, less is known about the mediating mechanisms explaining it. Based on a developmental mentalisation-based theoretical framework, childhood adversity compromises mentalising ability and attachment security, which in turn increase vulnerability to later stressors in adulthood.

objectiveThis study aimed to investigate the role of attachment and mentalising as potential mechanisms in the relationship between childhood maltreatment, self-harm and suicidality. PARTICIPANTS AND

settingWe recruited 907 adults from clinical and community settings in Greater London.

methodsThe study design was cross-sectional. Participants completed self-report questionnaires on retrospectively rated childhood trauma, and current attachment to the romantic partner, mentalising, self-harm, suicidal ideation and attempt. We used structural equation modelling to examine the data and conceptualized childhood maltreatment as a general factor in a confirmatory bifactor model.

resultsThe results showed that childhood maltreatment was both directly associated with self-harm and suicidality and indirectly via the pathways of attachment and mentalising.

conclusionsThese findings indicate that insecure attachment and impaired mentalising partially explain the association between childhood maltreatment, self-harm and suicidality. Clinically, they provide support for the potential of mentalisation-based therapy or other psychosocial interventions that aim to mitigate the risk of self-harm and suicidality among individuals who have experienced childhood maltreatment via increasing understanding of self and other mental states.

Indexed as

Child AbuseSelf-Injurious BehaviorSuicideAdultChildCross-Sectional StudiesHumansRetrospective StudiesSuicidal IdeationAttachmentChildhood traumaMentalisingNon-suicidal self-injury (NSSI)Structural equation modelSuicidality

Identifiers

PMID35313127
PMCPMC10466023

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.