Evidence map›Paper›PMID 35312352›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Biochemical and structural characterization of an aromatic ring-hydroxylating dioxygenase for terephthalic acid catabolism.

William M Kincannon, Michael Zahn, Rita Clare, Jessica Lusty Beech, Ari Romberg, James Larson, Brian Bothner, Gregg T Beckham, John E McGeehan, Jennifer L DuBois

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  11. Elucidating the Role of OACS environmental Au · 2024
    Article
  12. Understanding the stability of a plastic-degrading Rieske iron oxidoreductase system.Protein science : a publication of the Protein Society · 2024
    Article
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

William M KincannonDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0003-2392-2764
Michael ZahnCentre for Enzyme Innovation, University of Portsmouth, Portsmouth, PO1 2PY, United Kingdom.
Rita ClareDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0002-8643-3899
Jessica Lusty BeechDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0002-4212-6133
Ari RombergDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.
James LarsonDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.
Brian BothnerDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0003-1295-9609
Gregg T BeckhamBio-Optimized Technologies to Keep Thermoplastics out of Landfills and the Environment Consortium, Golden, CO 80401.ORCID 0000-0002-3480-212X
John E McGeehanCentre for Enzyme Innovation, University of Portsmouth, Portsmouth, PO1 2PY, United Kingdom.ORCID 0000-0002-6750-1462
Jennifer L DuBoisDepartment of Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0001-5593-3391

Funding

Understanding how heme and iron are metabolized by anaerobic commensal bacteria and host-microbiome communitiesR35GM136390 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jennifer L DuBois · 2020 to 2026
$2.2M
6 · The paper itself

Abstract

SignificanceMore than 400 million tons of plastic waste is produced each year, the overwhelming majority of which ends up in landfills. Bioconversion strategies aimed at plastics have emerged as important components of enabling a circular economy for synthetic plastics, especially those that exhibit chemically similar linkages to those found in nature, such as polyesters. The enzyme system described in this work is essential for mineralization of the xenobiotic components of poly(ethylene terephthalate) (PET) in the biosphere. Our description of its structure and substrate preferences lays the groundwork for in vivo or ex vivo engineering of this system for PET upcycling.

Indexed as

DioxygenasesPhthalic AcidsPlasticsPolyethylene TerephthalatesDioxygenasesPhthalic AcidsPlasticsPolyethylene Terephthalatesterephthalic acidoxygenaseplasticPoly(ethylene terephthalate)Rieske dioxygenaseterephthalate

Identifiers

PMID35312352
PMCPMC9060491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.