ArticleACS applied materials & interfaces2022
Self-Assembly of Soluplus in Aqueous Solutions: Characterization and Prospectives on Perfume Encapsulation.
Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Molecular Dynamics Simulation and MM/PBSA Analysis of α-Mangostin Stabilization in SoluplusInternational journal of molecular sciences · 2026Article
- Synergistic Enhancement of Diosgenin Dissolution and Bioavailability via Ternary Solid Dispersions and Self-Assembled Polymeric Micelles.Drug design, development and therapy · 2026Article
- Comparative Study of Dexamethasone-Loaded Thermoresponsive In Situ Gels and Polymeric Micelles for Ocular Drug Delivery.International journal of molecular sciences · 2025Article
- Mechanistic Investigation into the Phase Separation Behavior of Soluplus in the Presence of Biorelevant Media.Molecular pharmaceutics · 2025Article
- Insight into the Precipitation Inhibition of Polymers within Cocrystal Formulations in Solution Using Experimental and Molecular Modeling Techniques.Crystal growth & design · 2025Article
- SoluplusInternational journal of molecular sciences · 2025Review
- Antiparasitic Activities of Acyl Hydrazones from Cinnamaldehydes and Structurally Related Fragrances.Antibiotics (Basel, Switzerland) · 2024Article
- Soluplus-TPGS Mixed Micelles as a Delivery System for Brigatinib: Characterization and In Vitro Evaluation.ACS omega · 2024Article
- Efficient Improvement of Eugenol Water Solubility by Spray Drying Encapsulation in SoluplusPharmaceuticals (Basel, Switzerland) · 2024Article
- Preparation, Characterization, and Oral Bioavailability of Solid Dispersions ofInternational journal of molecular sciences · 2024Article
- Dual stimuli-responsive polymeric nanoparticles combining soluplus and chitosan for enhanced breast cancer targeting.RSC advances · 2024Article
- Co-Dispersion Delivery Systems with Solubilizing Carriers Improving the Solubility and Permeability of Cannabinoids (Cannabidiol, Cannabidiolic Acid, and Cannabichromene) fromPharmaceutics · 2023Article
- Transdermal Delivery of Glimepiride: A Novel Approach Using Nanomicelle-Embedded Microneedles.Pharmaceutics · 2023Article
- Preparation of Apixaban Solid Dispersion for the Enhancement of Apixaban Solubility and Permeability.Pharmaceutics · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soluplus is an amphiphilic graft copolymer intensively studied as a micellar solubilizer for drugs. An extensive characterization of the nanostructure of its colloidal aggregates is still lacking. Here, we provide insights into the polymer's self-assembly in water, and we assess its use as an encapsulating agent for fragrances. The self-assembly properties of Soluplus aqueous solutions were studied over a wide concentration range (1-70% w/w) by means of small-angle neutron scattering (SANS), differential scanning calorimetry, NMR, and rheometry. SANS analyses revealed the presence of polymeric micelles with a fuzzy surface interacting via a 2-Yukawa potential, up to 15% w/w polymer. Increasing the polymer concentration up to 55% w/w led to tightly packed micelles described according to the Teubner-Strey model. The ability of Soluplus to encapsulate seven perfume molecules, 2-phenyl ethanol, l-carvone, linalool, florhydral, β-citronellol, α-pinene, and
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.