Evidence map›Paper›PMID 35312085›Full record

ArticleClinical cardiology2022

Post-PCI quantitative flow ratio predicts 3-year outcome after rotational atherectomy in patients with heavily calcified lesions.

Wei You, Yuhe Zhou, Zhiming Wu, Peina Meng, Defeng Pan, Delu Yin, Song Yang, Xiangqi Wu, Fei Ye

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Wei YouDivision of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yuhe ZhouDivision of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhiming WuDivision of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Peina MengDivision of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Defeng PanDivision of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Delu YinDivision of Cardiology, The First People's Hospital of Lianyungang, Lianyungang, China.
Song YangDivision of Cardiology, Yixing People's Hospital, Yixing, China.
Xiangqi WuDivision of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Fei YeDivision of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.ORCID http://orcid.org/0000-0002-5651-3433
Nanjing Medical University · CNAnhui Medical University · CNJiangsu University · CNThe First People’s Hospital of Lianyungang · CNXuzhou Medical College · CN

Funding

Cardiocare Sponsored (CS) Optimized Antithrombotic Research Fund BJUHFCSOARF201801-13Nanjing Municipal Science and Technology Bureau 201803008
6 · The paper itself

Abstract

backgroundThe study sought to investigate the clinical predictive value of quantitative flow ratio (QFR) for the long-term outcome in patients with heavily calcified lesions who underwent percutaneous coronary intervention (PCI) following rotational atherectomy (RA).

methodsIn this retrospective study, 393 consecutive patients from 2009 to 2017 were enrolled. The QFR of the entire target vessel (QFRv) and the QFR of the stent plus 5 mm proximally and distally (in-segment) (QFRi) were measured. The primary endpoint was target lesion failure (TLF), including target lesion-cardiac death (TL-CD), target lesion-myocardial infarction (TL-MI), and clinically driven-target lesion revascularization (CD-TLR).

resultsA total of 224 patients with 224 calcified lesions completed the clinical follow-up, and 52 patients had TLF. There was no significant difference in QFRv post-PCI between non-TLF and TLF groups (p > .05). However, QFRi post PCI was significantly higher in the non-TLF group than in the TLF group. Multivariate Cox regression showed that QFRi post-PCI was an excellent predictor of TLF after a 3-year follow-up (HR 1.7E

conclusionsQFRi post-PCI showed a high predictive value for TLF for during a 3-year follow-up in patients who underwent PCI following RA; specifically, lower QFRi values post-PCI were associated with worse TLF.

Indexed as

Atherectomy, CoronaryCoronary Artery DiseaseDrug-Eluting StentsPercutaneous Coronary InterventionHumansRetrospective StudiesRisk FactorsTime FactorsTreatment Outcomecalcified lesionpatientspercutaneous coronary interventionquantitative flow ratiorotational atherectomy

Identifiers

PMID35312085
PMCPMC9045081
OpenAlexW4220857795

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.