Evidence map›Paper›PMID 35312026›Full record

ArticleActa dermato-venereologica2022

Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population.

Julie De Smedt, Sofie Van Kelst, Laudine Janssen, Vivien Marasigan, Veerle Boecxstaens, Marguerite Stas, Dirk Vanderschueren, Ipek Guler, Kris Bogaerts, Katleen Vandenberghe and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in Acta dermato-venereologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01748448 (Vitamin D Supplementation in Cutaneous Malignant Melanoma Outcome), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01748448 phase3completednot on this map

Vitamin D Supplementation in Cutaneous Malignant Melanoma Outcome

TypeinterventionalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2012 to 2022Enrolled436ConditionsCutaneous Malignant MelanomaArmsVitamin D, Placebo: Oil
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Julie De SmedtSchool of Biomedical sciences, Department of Oncology, Catholic University of Leuven, Herestraat 49, 3000 Leuven, Belgium. julie.desmedt@uzleuven.be.
Sofie Van Kelst
Laudine Janssen
Vivien Marasigan
Veerle Boecxstaens
Marguerite Stas
Dirk Vanderschueren
Ipek Guler
Kris Bogaerts
Katleen Vandenberghe
Oliver Bechter
Jaak Billen
Arjen Nikkels
Tine Strobbe
Gabriella Emri
Diether Lambrechts
Marjan Garmyn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D status is influenced by well-known determinants, but factors associated with low 25-hydroxyvitamin D levels in the cutaneous melanoma population are not well defined. The aim of this study was to confirm the well-known determinants and to assess new determinants for 25-hydroxyvitamin D levels in a cutaneous melanoma population. In a prospectively included cohort of 387 patients with cutaneous melanoma the association of 25-hydroxyvitamin D levels with sex, age, body mass index, time of blood withdrawal, Fitzpatrick phototype, vitamin D supplementation, score for intensity of lifetime sun exposure, smoking, education level, hair and skin colour, eye colour, total number of benign naevi, freckles and parameters of chronic sun damage was investigated. In addition, 25-hydroxyvitamin D levels were correlated with pathological parameters of the primary tumour and melanoma stage (8th edition of the American Joint Committee on Cancer (AJCC). Univariate and multivariate logistic regressions were performed using R software. The following factors had a significant effect on vitamin D status: body mass index, seasonal time of blood sampling, vitamin D supplementation, and a subtype of skin, and hair colour.

Indexed as

MelanomaSkin NeoplasmsCalcifediolCutaneous Malignant MelanomaHumansVitamin DVitamins25-hydroxyvitamin DCalcifediolVitamin DVitamins

Identifiers

PMID35312026
PMCPMC9609978

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.