Evidence map›Paper›PMID 35311575›Full record

ArticleMicrobiology spectrum2022

Comparison of Saliva and Midturbinate Swabs for Detection of SARS-CoV-2.

Jianyu Lai, Jennifer German, Filbert Hong, S-H Sheldon Tai, Kathleen M McPhaul, Donald K Milton, University of Maryland StopCOVID Research Group for the University of Maryland StopCOVID Research Group, Oluwasanmi Oladapo Adenaiye, Barbara Albert, P. Jacob Bueno de Mesquita, Yi Esparza, Aaron Kassman, Michael Lutchenkov, Dewansh Rastogi, Maria Schanz, Isabel Sierra Maldonado, Aditya Srikakulapu, Delwin Suraj, Faith Touré, Rhonda Washington-Lewis, Somayeh Youssefi, Stuart Weston, Matthew Frieman, Mara Cai, Ashok Agrawala

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. SARS-CoV-2 Variants May Affect Saliva RT-PCR Assay Sensitivity.The journal of applied laboratory medicine · 2024
    Article
  6. Article
  7. Scalable solutions for global health: the SalivaDirect model.Frontiers in cellular and infection microbiology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Saliva diagnostics: Salivaomics, saliva exosomics, and saliva liquid biopsy.Journal of the American Dental Association (1939) · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jianyu LaiDepartment of Epidemiology and Biostatistics, University of Maryland School of Public Health, College Park, Maryland, USA.ORCID 0000-0001-5705-0138
Jennifer GermanPublic Health Aerobiology and Biomarker Laboratory, Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, Maryland, USA.ORCID 0000-0003-3196-4083
Filbert HongPublic Health Aerobiology and Biomarker Laboratory, Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, Maryland, USA.ORCID 0000-0003-2289-5119
S-H Sheldon TaiPublic Health Aerobiology and Biomarker Laboratory, Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, Maryland, USA.
Kathleen M McPhaulPublic Health Aerobiology and Biomarker Laboratory, Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, Maryland, USA.ORCID 0000-0002-7008-142X
Donald K MiltonPublic Health Aerobiology and Biomarker Laboratory, Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, Maryland, USA.ORCID 0000-0002-0550-7834
University of Maryland StopCOVID Research Group for the University of Maryland StopCOVID Research Group, Oluwasanmi Oladapo Adenaiye, Barbara Albert, P. Jacob Bueno de Mesquita, Yi Esparza, Aaron Kassman, Michael Lutchenkov, Dewansh Rastogi, Maria Schanz, Isabel Sierra Maldonado, Aditya Srikakulapu, Delwin Suraj, Faith Touré, Rhonda Washington-Lewis, Somayeh Youssefi, Stuart Weston, Matthew Frieman, Mara Cai, Ashok Agrawala
University of Maryland, College Park · US

Funding

NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

Saliva is an attractive sample for detecting SARS-CoV-2. However, contradictory reports exist concerning the sensitivity of saliva versus nasal swabs. We followed close contacts of COVID-19 cases for up to 14 days from the last exposure and collected self-reported symptoms, midturbinate swabs (MTS), and saliva every 2 or 3 days. Ct values, viral load, and frequency of viral detection by MTS and saliva were compared. Fifty-eight contacts provided 200 saliva-MTS pairs, and 14 contacts (13 with symptoms) had one or more positive samples. Saliva and MTS had similar rates of viral detection (

Indexed as

COVID-19SARS-CoV-2HumansNasopharynxSalivaSpecimen HandlingCOVID-19midturbinate swabpolymerase chain reactionsalivaSARS-CoV-2

Identifiers

PMID35311575
PMCPMC9045394
OpenAlexW4220671203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.