Evidence map›Paper›PMID 35311570›Full record

ArticleMicrobiology spectrum2022

Vaginal

Si Chen, Xiaomeng Xue, Yingxuan Zhang, Huimin Zhang, Xuge Huang, Xiaofeng Chen, Gaopi Deng, Songping Luo, Jie Gao

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Increased vaginalmSystems · 2025
    Article
  4. Review
  5. The composition of lower genital tract microbiota correlates withFrontiers in cellular and infection microbiology · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Si Chen *The First Clinical College, Guangzhou University of Chinese Medicinegrid.411866.c, Guangzhou, Guangdong, China.ORCID 0000-0002-0661-966X
Xiaomeng Xue *The First Clinical College, Guangzhou University of Chinese Medicinegrid.411866.c, Guangzhou, Guangdong, China.
Yingxuan Zhang *The First Clinical College, Guangzhou University of Chinese Medicinegrid.411866.c, Guangzhou, Guangdong, China.
Huimin ZhangThe First Clinical College, Guangzhou University of Chinese Medicinegrid.411866.c, Guangzhou, Guangdong, China.
Xuge HuangThe First Clinical College, Guangzhou University of Chinese Medicinegrid.411866.c, Guangzhou, Guangdong, China.
Xiaofeng ChenThe First Clinical College, Guangzhou University of Chinese Medicinegrid.411866.c, Guangzhou, Guangdong, China.
Gaopi DengDepartment of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese, Guangzhou, Guangdong China.
Songping LuoDepartment of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese, Guangzhou, Guangdong China.
Jie GaoDepartment of Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese, Guangzhou, Guangdong China.ORCID 0000-0003-2203-8993
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous abortion (SA) has received more and more attention in light of its increasing incidence. However, the causes and pathogenesis of SA remain largely unknown, especially for those without any pathological features. In this study, we characterized the vaginal microbiota diversity and composition of pregnant women in their first trimester and evaluated the association between the vaginal microbiota and SA before 12 weeks of gestation. Participants' bacterial profiles were analyzed by 16S rRNA gene sequencing in the V3-V4 regions at 5-8 weeks of gestation. A total of 48 patients with SA at 12 weeks of gestation were included as the study group, while 116 women with normal pregnancies (NPs) were included as a control group. The results indicated that the richness of the vaginal microbiome in SA patients was higher (Chao1,

Indexed as

Abortion, SpontaneousActinobacteriaFemaleHumansPregnancyPregnancy Trimester, FirstProspective StudiesRNA, Ribosomal, 16SVaginaRNA, Ribosomal, 16S16S rRNAApotobiummachine learningspontaneous abortionvaginal microbiota

Identifiers

PMID35311570
PMCPMC9045190
OpenAlexW4220864302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.