Evidence map›Paper›PMID 35311531›Full record

ArticlemBio2022

Analysis of mRNA Decay Intermediates in Bacillus subtilis 3' Exoribonuclease and RNA Helicase Mutant Strains.

Shivani Chhabra, Zachary F Mandell, Bo Liu, Paul Babitzke, David H Bechhofer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Structural insights into RNA recognition by theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Analysis of 3'-seq data from multiplebioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shivani Chhabra *Icahn School of Medicine at Mount Sinaigrid.59734.3c, Department of Pharmacological Sciences, New York, New York, USA.
Zachary F Mandell *The Pennsylvania State University, Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, University Park, Pennsylvania, USA.
Bo LiuIcahn School of Medicine at Mount Sinaigrid.59734.3c, Department of Pharmacological Sciences, New York, New York, USA.
Paul BabitzkeThe Pennsylvania State University, Department of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, University Park, Pennsylvania, USA.ORCID 0000-0003-2481-1062
David H BechhoferIcahn School of Medicine at Mount Sinaigrid.59734.3c, Department of Pharmacological Sciences, New York, New York, USA.
Icahn School of Medicine at Mount Sinai · USPennsylvania State University · US

Funding

Regulation of transcription elongationR01GM098399 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BABITZKE, PAUL L · 2012 to 2024
$3.6M
Mechanism of 3' exonucleolytic mRNA turnover in Bacillus subtilisR01GM125655 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BECHHOFER, DAVID H · 2018 to 2021
$1.4M
HHS | National Institutes of Health (NIH) GM098399HHS | National Institutes of Health (NIH) GM125655NIGMS NIH HHS R01 GM098399NIGMS NIH HHS R01 GM125655
6 · The paper itself

Abstract

The Bacillus subtilis genome encodes four 3' exoribonucleases: polynucleotide phosphorylase (PNPase), RNase R, RNase PH, and YhaM. Previous work showed that PNPase, encoded by the

Indexed as

Bacillus subtilisExoribonucleasesRNA HelicasesRNA, MessengerRNA StabilityExoribonucleasesRNA HelicasesRNA, Messenger3′ exoribonucleasesBacillus subtilismRNA decayPNPaseRNA helicaseTerm-seqtranscriptomics

Identifiers

PMID35311531
PMCPMC9040804
OpenAlexW4221047944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.