Evidence map›Paper›PMID 35311509›Full record

ArticleApplied and environmental microbiology2022

Increased Butyrate Production in Clostridium saccharoperbutylacetonicum from Lignocellulose-Derived Sugars.

Saskia Tabea Baur, Sidsel Markussen, Francesca Di Bartolomeo, Anja Poehlein, Anna Baker, Elizabeth R Jenkinson, Rolf Daniel, Alexander Wentzel, Peter Dürre

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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  4. Modulation ofFrontiers in genetics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Saskia Tabea BaurUniversity of Ulmgrid.6582.9, Institute of Microbiology and Biotechnology, Ulm, Germany.ORCID 0000-0002-7186-9163
Sidsel MarkussenSINTEF Industry, Department of Biotechnology and Nanomedicine, Trondheim, Norway.
Francesca Di BartolomeoSINTEF Industry, Department of Biotechnology and Nanomedicine, Trondheim, Norway.
Anja PoehleinUniversity of Göttingen, Department of Genomic and Applied Microbiology, Institute of Microbiology and Genetics, Göttingen, Germany.ORCID 0000-0002-2473-6202
Anna BakerBiocleave Ltd., Abingdon, United Kingdom.
Elizabeth R JenkinsonBiocleave Ltd., Abingdon, United Kingdom.
Rolf DanielUniversity of Göttingen, Department of Genomic and Applied Microbiology, Institute of Microbiology and Genetics, Göttingen, Germany.ORCID 0000-0002-8646-7925
Alexander WentzelSINTEF Industry, Department of Biotechnology and Nanomedicine, Trondheim, Norway.
Peter DürreUniversity of Ulmgrid.6582.9, Institute of Microbiology and Biotechnology, Ulm, Germany.
SINTEF · NOUniversität Ulm · DEUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Butyrate is produced by chemical synthesis based on crude oil, produced by microbial fermentation, or extracted from animal fats (M. Dwidar, J.-Y. Park, R. J. Mitchell, and B.-I. Sang, The Scientific World Journal, 2012:471417, 2012, https://doi.org/10.1100/2012/471417). Butyrate production by anaerobic bacteria is highly favorable since waste or sustainable resources can be used as the substrates. For this purpose, the native hyper-butanol producer Clostridium saccharoperbutylacetonicum N1-4(HMT) was used as a chassis strain due to its broad substrate spectrum. BLASTp analysis of the predicted proteome of C. saccharoperbutylacetonicum N1-4(HMT) resulted in the identification of gene products potentially involved in acetone-butanol-ethanol (ABE) fermentation. Their participation in ABE fermentation was either confirmed or disproven by the parallel production of acids or solvents and the respective transcript levels obtained by transcriptome analysis of this strain. The genes encoding phosphotransacetylase (

Indexed as

ButyratesPetroleum1-ButanolAcetoneButanolsClostridiumEthanolFermentationGlucoseLigninSugars1-ButanolAcetoneButanolsButyratesEthanolGlucoseLigninlignocellulosePetroleumSugarsbutyrateClostridium saccharoperbutylacetonicumExcellofermentationlignocellulosic sugarsmetabolic engineeringsolventstranscriptome analysis

Identifiers

PMID35311509
PMCPMC9004393
OpenAlexW4220913198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.