Evidence map›Paper›PMID 35311403›Full record

ArticleTherapeutic advances in respiratory disease

Prognostic factors and outcomes in COVID-19 patients requiring prolonged mechanical ventilation: a retrospective cohort study.

Roman Melamed, Francisco Paz, Stacy Jepsen, Claire Smith, Ramiro Saavedra, Maximilian Mulder, Adnan Masood, Joshua Huelster, Lisa Kirkland, Alena Guenther and 1 more

Abstract read
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  10. Predictors of prolonged ventilator weaning and mortality in critically ill patients with COVID-19.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
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  12. Prognostic performance of the Age, PaOTherapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roman MelamedAbbott Northwestern Hospital, Minneapolis, MN 55407-3799, USA.ORCID 0000-0001-6187-1414
Francisco PazAbbott Northwestern Hospital, Minneapolis, MN, USA.
Stacy JepsenAbbott Northwestern Hospital, Minneapolis, MN, USA.
Claire SmithAllina Health, Minneapolis, MN, USA.
Ramiro SaavedraAbbott Northwestern Hospital, Minneapolis, MN, USA.
Maximilian MulderAbbott Northwestern Hospital, Minneapolis, MN, USA.
Adnan MasoodAbbott Northwestern Hospital, Minneapolis, MN, USA.
Joshua HuelsterAbbott Northwestern Hospital, Minneapolis, MN, USA.
Lisa KirklandAbbott Northwestern Hospital, Minneapolis, MN, USA.
Alena GuentherAllina Health, Minneapolis, MN, USA.
Lori BolandAllina Health, Minneapolis, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical ventilation (MV) in coronavirus disease 2019 (COVID-19) patients is associated with high mortality and extensive resource utilization. The aim of this study was to investigate prognostic factors and outcomes associated with prolonged mechanical ventilation (PMV) in COVID-19 patients.

methodsThis was a retrospective cohort study of COVID-19 patients requiring invasive MV who were hospitalized between 1 March 2020 and 30 June 2021 in the intensive care units (ICUs) of three referral hospitals belonging to a single health system. Data were extracted from electronic health records. PMV was defined as  > 17 days of MV.

resultsOf 355 patients studied, 86 (24%) required PMV. PMV patients had lower PaO

conclusionPMV is commonly required in COVID-19 patients with respiratory failure. Despite the higher need for critical care interventions and LOS, more than half of the PMV cohort survived to hospital discharge. Higher PaO

Indexed as

COVID-19Cohort StudiesHumansPrognosisRespiration, ArtificialRetrospective StudiesCOVID-19 virus diseaseintensive care unitslength of staymechanical ventilationrespiratory failure

Identifiers

PMID35311403
PMCPMC8935584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.