Evidence map›Paper›PMID 35311238›Full record

ArticleFrontiers in endocrinology2022

Vitamin D Status and All-Cause Mortality in Patients With Type 2 Diabetes in China.

Yuxin Fan, Li Ding, Yalan Zhang, Hua Shu, Qing He, Jingqiu Cui, Gang Hu, Ming Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yuxin FanDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Li DingDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Yalan ZhangDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Hua ShuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Qing HeDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Jingqiu CuiDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Gang HuChronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, United States.
Ming LiuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Medical University General Hospital · CNPennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Objective: To assess the association between vitamin D status and all-cause mortality among type 2 diabetes patients. Research Design and Methods: We prospectively followed 1,291 participants with type 2 diabetes aged 20-80 years during 2013-2018. Cox proportional hazard regression models were used to estimate the association between different vitamin D status and all-cause mortality risk among hospitalized patients with type 2 diabetes. Results: During a median follow-up of 4.15 years (5,365 person-years in total), 61 cases of death were identified. Multivariable-adjusted hazard ratios (HRs) for all-cause mortality across the quartiles of baseline circulating 25-hydroxy vitamin D (25-OH vitamin D) were 2.70 [95% confidence interval (CI) 1.12-6.54], 1.00, 1.39 (95% CI 0.53-3.65), 2.31 (95% CI 0.96-5.54), respectively. Multivariable-adjusted HRs for all-cause mortality by different groups of baseline 25-OH vitamin D concentrations (<25, 25-49, 50-100, and ≥100 nmol/L) were 1.31 (95% CI 0.58-2.96), 0.94 (95% CI 0.47-1.87), 1.00, and 3.58 (95% CI 1.43-8.98), respectively. Conclusions: Very low or high concentrations of vitamin D may be associated with a higher risk of all-cause mortality among patients with type 2 diabetes.

Indexed as

Diabetes Mellitus, Type 2ChinaHumansRisk FactorsVitamin DVitaminsVitamin DVitamins1,25-(OH)2D325-OH vitamin Dall-cause mortalitytype 2 diabetesvitamin D

Identifiers

PMID35311238
PMCPMC8931658
OpenAlexW4214852496

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.