Evidence map›Paper›PMID 35310988›Full record

ArticleFrontiers in cardiovascular medicine2022

Dose Reduction of Dynamic Computed Tomography Myocardial Perfusion Imaging by Tube Voltage Change: Investigation in a Swine Model.

Wenlei Geng, Yang Gao, Na Zhao, Hankun Yan, Wei Ma, Yunqiang An, Liujun Jia, Bin Lu

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Research Progress in Imaging Evaluation of Myocardial Microcirculation.International journal of general medicine · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenlei GengDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Yang GaoDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Na ZhaoDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Hankun YanDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Wei MaDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Yunqiang AnDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Liujun JiaAnimal Experimental Center, Beijing Key Laboratory of Pre-Clinical Research and Evaluation for Cardiovascular Implant Materials, State Key Laboratory of Cardiovascular Disease, Beijing, China.
Bin LuDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It is unclear whether tube voltage influences the measurement of perfusion parameters. The present study sought to evaluate the influence of tube voltage change on myocardial blood flow (MBF) measurements in dynamic computed tomography myocardial perfusion imaging (CTP). Methods and Results: Seven swine [mean weight 55.8 kg ± 1.6 (standard deviation)] underwent rest and stress dynamic CTP with tube voltages of 100 and 70 kV. The image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), radiation dose and MBF value were compared. The 70 kV images had higher CT attenuation and higher image noise (27.9 ± 2.4 vs. 21.5 ± 1.9, Conclusion: Dynamic CTP using 70 kV instead of 100 kV does not substantially influence the MBF value but significantly reduces the radiation dose. Additional research is required to investigate the clinical significance of this change.

Indexed as

cardiac imaging techniquescomputed tomographyimage quality enhancementmyocardial perfusionradiation dosage

Identifiers

PMID35310988
PMCPMC8927626

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.