Evidence map›Paper›PMID 35310820›Full record

ArticleJHEP reports : innovation in hepatology2022

A systematic review of auxiliary liver transplantation of small-for-size grafts in patients with chronic liver disease.

Daniel Azoulay, Cyrille Feray, Chetana Lim, Chady Salloum, Maria Conticchio, Daniel Cherqui, Antonio Sa Cunha, René Adam, Eric Vibert, Didier Samuel and 2 more

Open access · goldAbstract read
In one paragraph

Article in JHEP reports : innovation in hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Whole pediatric liver graft in modified RAPID transplantation for unresectable colorectal liver metastases.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  3. Article
  4. Review
  5. Recipient-Donor Sex Constellation in Liver Transplantation for Hepatocellular Carcinoma-An ELTR Study.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Daniel AzoulayDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Cyrille FerayINSERM, Université Paris-Saclay, UMRS 1193, Physiopathogénèse et traitement des maladies du Foie, FHU Hepatinov, Villejuif, France.
Chetana LimDepartment of Surgery, Pitié-Salpêtrière Hospital, Université Paris-Descartes, Paris, France.
Chady SalloumDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Maria ConticchioDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Daniel CherquiDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Antonio Sa CunhaDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
René AdamDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Eric VibertDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Didier SamuelINSERM, Université Paris-Saclay, UMRS 1193, Physiopathogénèse et traitement des maladies du Foie, FHU Hepatinov, Villejuif, France.
Marc Antoine AllardDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Nicolas GolseDepartment of Surgery, Paul-Brousse Hospital, Assistance Publique Hôpitaux de Paris, Centre Hépato-Biliaire, Villejuif, France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & Aims: The shortage of liver grafts continues to worsen. Because the expanded use of small-for-size grafts (SFSGs) would substantially alleviate this shortage, we aimed to analyse the available knowledge on auxiliary liver transplantation (ALT) with SFSGs in patients with chronic liver disease (CLD) to identify opportunities to develop ALT with SFSGs in patients with CLD. Methods: This is a systematic review on ALT using SFSGs in patients with CLD. The review was completed by updates obtained from the authors of the retained reports. Results: Heterotopic ALT was performed in 26 cases between 1980 and 2017, none for SFGS Conclusions: Despite high postoperative morbidity, and highly reported technical variability, the APOLT technique is a promising technique to use SFSGs in patients with CLD, achieving satisfactory long-term results. The results need to be confirmed on a larger scale, and a standardised technique could lead to even better results. Lay summary: At the cost of a high postoperative morbidity, the long-term results of APOLT for small-for-size grafts are good. Standardisation of the procedure and of portal modulation remain needed.

Indexed as

ALT, auxiliary liver transplantationAOLT, auxiliary orthotopic liver transplantationAPOLT, auxiliary partial orthotopic liver transplantationAuxiliary liver transplantationChronic liver diseaseCLD, chronic liver diseaseDouble equipoiseHALT, heterotopic auxiliary liver transplantationHeterotopic liver transplantationIDEAL, Idea, Development, Exploration, Assessment, and Long-term follow-upLiver transplantationLiving-related liver transplantationLRLT, living-related liver transplantationLT, liver transplantationMELD, model for end-stage liver diseaseOrgan shortageOrthotopic liver transplantationPICO, Population, Intervention, Comparison, and OutcomePRISMA, Preferred Reporting Items for Systematic Reviews and Meta-AnalysesSFSG, small-for-size graftSFSS, small-for-size syndromeSmall-for-size graftSmall-for-size syndromeSplit liver transplantationSystematic review

Identifiers

PMID35310820
PMCPMC8927838
OpenAlexW4211029368

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.