Evidence map›Paper›PMID 35310764›Full record

ArticleDEN open2022

Photoacoustic imaging of fresh human surgically and endoscopically resected gastrointestinal specimens.

Hiroaki Ikematsu, Miya Ishihara, Shinpei Okawa, Tatsunori Minamide, Tomohiro Mitsui, Takeshi Kuwata, Masaaki Ito, Takahiro Kinoshita, Takeo Fujita, Tomonori Yano and 5 more

Abstract read
In one paragraph

Article in DEN open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hiroaki IkematsuDivision of Science and Technology for Endoscopy Exploratory Oncology Research and Clinical Trial Center National Cancer Center Chiba Japan.ORCID https://orcid.org/0000-0001-9840-4588
Miya IshiharaDepartment of Medical Engineering National Defense Medical College Saitama Japan.
Shinpei OkawaDepartment of Medical Engineering National Defense Medical College Saitama Japan.
Tatsunori MinamideDepartment of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba Japan.
Tomohiro MitsuiDepartment of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba Japan.
Takeshi KuwataDepartment of Pathology and Clinical Laboratories National Cancer Center Hospital East Chiba Japan.
Masaaki ItoDepartment of Colorectal Surgery National Cancer Center Hospital East Chiba Japan.ORCID https://orcid.org/0000-0002-1101-2707
Takahiro KinoshitaDepartment of Gastric Surgery National Cancer Center Hospital East Chiba Japan.
Takeo FujitaDepartment of Esophageal Surgery National Cancer Center Hospital East Chiba Japan.
Tomonori YanoDepartment of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba Japan.
Toshihiko OmoriMedical Systems Research & Development Center Research & Development Management Headquarters FUJIFILM Corporation Kanagawa Japan.
Satoshi OzawaMedical Systems Research & Development Center Research & Development Management Headquarters FUJIFILM Corporation Kanagawa Japan.
Dai MurakoshiMedical Systems Research & Development Center Research & Development Management Headquarters FUJIFILM Corporation Kanagawa Japan.
Kaku IrisawaMedical Systems Research & Development Center Research & Development Management Headquarters FUJIFILM Corporation Kanagawa Japan.
Atsushi OchiaiExploratory Oncology Research and Clinical Trial Center National Cancer Center Chiba Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Photoacoustic (PA) imaging is a novel noninvasive technique that offers high-contrast tomographic imaging with ultrasound-like resolution at depths of centimeters, enabling visualization of deep small vessels. The aim of this pilot study was to survey the characteristics of deep vessel networks in the mucosa of neoplastic gastrointestinal (GI) lesions using PA imaging. Methods: Specimens of patients who had undergone surgical and endoscopic resection for GI lesions were included in this study. The PA/ultrasound imaging system for clinical research is characterized by a technology that can superimpose a PA image over an ultrasound image. Three-dimensional PA images were acquired for the resected specimen before fixation. The stomach and colon of live pigs were incised, and the walls were scanned from the mucosa. Results: A total of 32 specimens (nine esophageal, 12 gastric, 11 colorectal) were scanned. The pathological diagnoses were adenomas ( Conclusion: Our study confirmed that the deep vessel networks of neoplastic GI lesions were visible by PA imaging.

Indexed as

deep vessel networkgastrointestinal lesionsoptoacoustic imaging

Identifiers

PMID35310764
PMCPMC8828192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.