Evidence map›Paper›PMID 35310743›Full record

ReviewDEN open2022

Endoscopic diagnosis of chronic diarrhea.

Yoshikazu Kinoshita, Ryusuke Ariyoshi, Seiji Fujigaki, Katsuhide Tanaka, Teruhisa Morikawa, Tsuyoshi Sanuki

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in DEN open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05470946 (Evaluation of the Diagnostic Role of Enteroscopy in Small Intestinal Diseases at Al-Rajhi University Hospital), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05470946 naunknown statusnot on this map

Evaluation of the Diagnostic Role of Enteroscopy in Small Intestinal Diseases at Al-Rajhi University Hospital

TypeinterventionalSponsorAssiut UniversityRan2022 to 2024Enrolled50ConditionsSmall Intestine DiseaseArmsDouble balloon enteroscopy
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Bile acid diarrhea.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  4. Article
  5. Article
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yoshikazu KinoshitaDepartment of Medicine Hyogo Brain and Heart Center Hyogo Japan.ORCID https://orcid.org/0000-0001-5708-985X
Ryusuke AriyoshiDepartment of Gastroenterology Steel Memorial Hirohata Hospital Hyogo Japan.
Seiji FujigakiDepartment of Gastroenterology Steel Memorial Hirohata Hospital Hyogo Japan.
Katsuhide TanakaDepartment of Gastroenterology Steel Memorial Hirohata Hospital Hyogo Japan.
Teruhisa MorikawaDepartment of Gastroenterology Steel Memorial Hirohata Hospital Hyogo Japan.
Tsuyoshi SanukiDepartment of Gastroenterology Steel Memorial Hirohata Hospital Hyogo Japan.
Nippon Steel Yawata Memorial Hospital · JPHyogo Brain and Heart Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of chronic diarrhea in the general population is reported to be 4%-5%. Since various pathological conditions cause diarrheal symptoms, etiological diagnosis of chronic diarrhea is difficult in many cases. Medical history taking, physical examinations, and laboratory testing are not adequately sensitive or specific, thus a colonoscopic investigation is frequently employed for etiological evaluation. However, for cases with non-bloody chronic diarrhea, the diagnostic yield of a colonoscopy procedure is reported to be not high enough. Furthermore, endoscopically identifiable findings are not adequately specific for the diagnosis of diarrheal disease, except for inflammatory bowel disease, while microscopic colitis, amyloidosis, eosinophilic gastroenteritis, celiac disease, and bile acid diarrhea are difficult to definitively diagnose using endoscopic findings. Thus, a histopathological examination of biopsy samples obtained with endoscopy is critically important. Endoscopists should consider obtaining biopsy samples from even normal-appearing gastrointestinal mucosa for chronic diarrhea diagnosis.

Indexed as

amyloidosisbile acid diarrheaceliac diseasecollagenous colitiseosinophilic gastroenteritis

Identifiers

PMID35310743
PMCPMC8828214
OpenAlexW3202554928

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.