Evidence map›Paper›PMID 35310513›Full record

ArticleMicrosystems & nanoengineering2022

Self-assembled microtubular electrodes for on-chip low-voltage electrophoretic manipulation of charged particles and macromolecules.

Apratim Khandelwal, Nagendra Athreya, Michael Q Tu, Lukas L Janavicius, Zhendong Yang, Olgica Milenkovic, Jean-Pierre Leburton, Charles M Schroeder, Xiuling Li

Abstract read
In one paragraph

Article in Microsystems & nanoengineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. One-step rolling fabrication of VOScience advances · 2023
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Apratim KhandelwalDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.ORCID 0000-0001-8181-6084
Nagendra AthreyaDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.
Michael Q TuDepartment of Chemical Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.
Lukas L JanaviciusDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.
Zhendong YangDepartment of Electrical and Computer Engineering, Microelectronics Research Center, University of Texas, Austin, TX 78758 USA.
Olgica MilenkovicDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.
Jean-Pierre LeburtonDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.
Charles M SchroederDepartment of Chemical Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.
Xiuling LiDepartment of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801 USA.ORCID 0000-0003-3698-5182

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On-chip manipulation of charged particles using electrophoresis or electroosmosis is widely used for many applications, including optofluidic sensing, bioanalysis and macromolecular data storage. We hereby demonstrate a technique for the capture, localization, and release of charged particles and DNA molecules in an aqueous solution using tubular structures enabled by a strain-induced self-rolled-up nanomembrane (S-RuM) platform. Cuffed-in 3D electrodes that are embedded in cylindrical S-RuM structures and biased by a constant DC voltage are used to provide a uniform electrical field inside the microtubular devices. Efficient charged-particle manipulation is achieved at a bias voltage of <2-4 V, which is ~3 orders of magnitude lower than the required potential in traditional DC electrophoretic devices. Furthermore, Poisson-Boltzmann multiphysics simulation validates the feasibility and advantage of our microtubular charge manipulation devices over planar and other 3D variations of microfluidic devices. This work lays the foundation for on-chip DNA manipulation for data storage applications.

Indexed as

Electrical and electronic engineeringMaterials scienceMicrofluidics

Identifiers

PMID35310513
PMCPMC8882674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.