Evidence map›Paper›PMID 35310497›Full record

ArticleChemical science2022

Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation.

Gabriel A Braun, Alexander J Dear, Kalyani Sanagavarapu, Henrik Zetterberg, Sara Linse

Abstract read
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
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  8. Article
  9. Amyloid-β modulates the phase separation and aggregation of α-synuclein.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Biomarkers Unveiling the Interplay of Mind, Nervous System, and Immunity.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Heterotypic Seeding Generates Mixed Amyloid Polymorphs.bioRxiv : the preprint server for biology · 2024
    Article
  20. The AβFrontiers in cellular neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel A BraunBiochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se.ORCID https://orcid.org/0000-0002-9105-5757
Alexander J DearBiochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se.ORCID https://orcid.org/0000-0003-3055-607X
Kalyani SanagavarapuBiochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.
Sara LinseBiochemistry and Structural Biology, Lund University Lund Sweden sara.linse@biochemistry.lu.se.ORCID https://orcid.org/0000-0001-9629-7109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathology of Alzheimer's disease is connected to the aggregation of β-amyloid (Aβ) peptide, which

Identifiers

PMID35310497
PMCPMC8864715

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.