Evidence map›Paper›PMID 35310495›Full record

ArticleChemical science2022

Polycyclic heteroaromatics

Eun Kee Cho, Phong K Quach, Yunfei Zhang, Jae Hun Sim, Tristan H Lambert

Abstract read
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. A Potassium Base-Promoted Intramolecular Enolate-Olefin Metathesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. Article
  5. Article
  6. Hydrazine-Catalysed Ring-Opening Metathesis Polymerization Of Cyclobutenes.Angewandte Chemie (International ed. in English) · 2024
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eun Kee ChoDepartment of Chemistry and Chemical Biology, Cornell University Ithaca New York 14853 USA tristan.lambert@cornell.edu.
Phong K QuachDepartment of Chemistry and Chemical Biology, Cornell University Ithaca New York 14853 USA tristan.lambert@cornell.edu.
Yunfei ZhangDepartment of Chemistry and Chemical Biology, Cornell University Ithaca New York 14853 USA tristan.lambert@cornell.edu.
Jae Hun SimDepartment of Chemistry and Chemical Biology, Cornell University Ithaca New York 14853 USA tristan.lambert@cornell.edu.
Tristan H LambertDepartment of Chemistry and Chemical Biology, Cornell University Ithaca New York 14853 USA tristan.lambert@cornell.edu.ORCID https://orcid.org/0000-0002-7720-3290

Funding

CATALYTIC PLATFORMS USING AROMATIC IONS AND OTHER CHARGED SPECIESR35GM127135 · NIGMS · CORNELL UNIVERSITY · PI Tristan H Lambert · 2018 to 2026
$4.4M
NIGMS NIH HHS R35 GM127135
6 · The paper itself

Abstract

The use of hydrazine-catalyzed ring-closing carbonyl-olefin metathesis (RCCOM) to synthesize polycyclic heteroaromatic (PHA) compounds is described. In particular, substrates bearing Lewis basic functionalities such as pyridine rings and amines, which strongly inhibit acid catalyzed RCCOM reactions, are shown to be compatible with this reaction. Using 5 mol% catalyst loadings, a variety of PHA structures can be synthesized from biaryl alkenyl aldehydes, which themselves are readily prepared by cross-coupling.

Identifiers

PMID35310495
PMCPMC8864716

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.