Evidence map›Paper›PMID 35310400›Full record

ArticleFrontiers in microbiology2021

Nasal Microbiome Change During and After Exacerbation in Asthmatic Children.

Tsunglin Liu, Cheng-Han Lin, Yi-Lin Chen, Shuen-Lin Jeng, Hui-Ju Tsai, Chung-Liang Ho, Wen-Shuo Kuo, Miao-Hsi Hsieh, Pei-Chi Chen, Lawrence Shih-Hsin Wu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Tsunglin LiuDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan.
Cheng-Han LinDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan.
Yi-Lin ChenMolecular Diagnostic Laboratory, Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan.
Shuen-Lin JengDepartment of Statistics, Center for Innovative Fin Tech Business Models, Institute of Data Science, National Cheng Kung University, Tainan, Taiwan.
Hui-Ju TsaiInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Chung-Liang HoMolecular Diagnostic Laboratory, Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan.
Wen-Shuo KuoCenter of Allergy, Immunology, and Microbiome (AIM), China Medical University Children's Hospital, Taichung, Taiwan.
Miao-Hsi HsiehCenter of Allergy, Immunology, and Microbiome (AIM), China Medical University Children's Hospital, Taichung, Taiwan.
Pei-Chi ChenCenter of Allergy, Immunology, and Microbiome (AIM), China Medical University Children's Hospital, Taichung, Taiwan.
Lawrence Shih-Hsin WuCenter of Allergy, Immunology, and Microbiome (AIM), China Medical University Children's Hospital, Taichung, Taiwan.
Jiu-Yao WangCenter of Allergy, Immunology, and Microbiome (AIM), China Medical University Children's Hospital, Taichung, Taiwan.
China Medical University · TWNational Cheng Kung University · TWNational Cheng Kung University Hospital · TWNational Health Research Institutes · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airway and gut microbiota are important in asthma pathogenesis. Although several studies have revealed distinct microbiota in asthmatic airways at baseline compared to healthy controls, limited studies compared microbiota during acute exacerbation (AE) and in the recovery phase (RP) in the same asthmatic children. We aim to investigate association between microbiota and asthma status in children and explore their relationship with clinical features of asthma. We recruited 56 asthmatic children and investigated their nasal, throat, and stool microbiota during AE and in the RP. Totally, 320 samples were subjected to 16S rRNA sequencing. Although the microbial communities were clearly separated by body site, within each site the overall communities during AE and in the RP could not be distinguished. Most nasal microbiota were dominated by only one or two of six bacterial genera. The domination was associated with mite allergy and patient age only during AE but not in the RP. When moving into RP, the relative abundance of

Indexed as

acute exacerbationchildhood asthmamite allergynasal microbiotarecovery phase

Identifiers

PMID35310400
PMCPMC8931732
OpenAlexW4214945648

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.