Evidence map›Paper›PMID 35310367›Full record

ReviewCurrent dermatology reports2022

Neutrophilic Dermatoses: a Clinical Update.

Emma H Weiss, Christine J Ko, Thomas H Leung, Robert G Micheletti, Arash Mostaghimi, Sarika M Ramachandran, Misha Rosenbach, Caroline A Nelson

Abstract readReview
In one paragraph

Review in Current dermatology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Oral Manifestations of Sweet Syndrome in a Child: A Case Report.International journal of clinical pediatric dentistry · 2026
    Article
  4. Article
  5. Erosive pustular dermatosis of the lower legs (EPDL): A rarely diagnosed neutrophilic dermatosis of the elderly.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Review
  6. Ibrutinib-induced Sweet syndrome.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. A Case of Sweet's Syndrome Presenting With Tongue Ulcerations.The Australasian journal of dermatology · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emma H WeissDepartment of Dermatology, Yale School of Medicine, New Haven, CT USA.
Christine J KoDepartment of Dermatology, Yale School of Medicine, New Haven, CT USA.
Thomas H LeungDepartment of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA.
Robert G MichelettiDepartment of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA.
Arash MostaghimiDepartment of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA USA.
Sarika M RamachandranDepartment of Dermatology, Yale School of Medicine, New Haven, CT USA.
Misha RosenbachDepartment of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA.
Caroline A NelsonDepartment of Dermatology, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0002-0863-6797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of Review: Neutrophilic dermatoses are defined by the presence of a sterile neutrophilic infiltrate on histopathology. This review focuses on the pathogenesis, epidemiology, clinicopathological features, diagnosis, and management of four disorders: Sweet syndrome, pyoderma gangrenosum, Behçet syndrome, and neutrophilic eccrine hidradenitis. Recent Findings: Recent studies have provided insight into the complex pathogenesis of neutrophilic dermatoses. Evidence supports an intricate interplay of abnormal neutrophil function and inflammasome activation, malignant transformation into dermal infiltrating neutrophils, and genetic predisposition. Summary: Neutrophilic dermatoses have diverse cutaneous and extracutaneous manifestations and may be associated with significant morbidity and mortality. Common underlying associations include infectious, inflammatory, and neoplastic disorders, as well as drug reactions. Emerging diagnostic and therapeutic frameworks identify an expanding role for biologic and targeted anti-inflammatory therapies.

Indexed as

Acute febrile neutrophilic dermatosisBehçet diseaseNeutrophilic dermatosisNeutrophilic eccrine hidradenitisPyoderma gangrenosumSweet syndrome

Identifiers

PMID35310367
PMCPMC8924564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.