Evidence map›Paper›PMID 35310361›Full record

ReviewBioactive materials2022

Bacterial extracellular vesicles as bioactive nanocarriers for drug delivery: Advances and perspectives.

Han Liu, Qin Zhang, Sicheng Wang, Weizong Weng, Yingying Jing, Jiacan Su

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed.

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  4. Towards a Scalable Production ofInternational journal of molecular sciences · 2026
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Han LiuInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Qin ZhangInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Sicheng WangInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Weizong WengInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Yingying JingInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.
Jiacan SuInstitute of Translational Medicine, Shanghai University, Shanghai, 200444, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanosized extracellular vesicles derived from bacteria contain diverse cargo and transfer intercellular bioactive molecules to cells. Due to their favorable intercellular interactions, cell membrane-derived bacterial extracellular vesicles (BEVs) have great potential to become novel drug delivery platforms. In this review, we summarize the biogenesis mechanism and compositions of various BEVs. In addition, an overview of effective isolation and purification techniques of BEVs is provided. In particular, we focus on the application of BEVs as bioactive nanocarriers for drug delivery. Finally, we summarize the advances and challenges of BEVs after providing a comprehensive discussion in each section. We believe that a deeper understanding of BEVs will open new avenues for their exploitation in drug delivery applications.

Indexed as

Bacterial extracellular vesiclesBioactive nanocarriersDrug deliveryIsolation and purification

Identifiers

PMID35310361
PMCPMC8892084

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.