Evidence map›Paper›PMID 35310307›Full record

ArticleClinical case reports2022

Cyclosporine A therapy of chronic lymphoblastic leukemia-related pancytopenia: A case report.

Mengying Wang, Ruoyu Meng, Yan Gao, Junxia Huang, Tianlan Li, Chunxia Mao, Shanshan Liu, Yujie Xu, Han Xu, Xianqi Feng

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Mengying WangDepartment of Hematology Faculty of Medicine Qingdao University The Affiliated Hospital of Qingdao University Qingdao China.ORCID https://orcid.org/0000-0002-7770-4781
Ruoyu MengDepartment of Physiology Chonbuk National University Medical School Jeonju Korea.
Yan GaoDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Junxia HuangDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Tianlan LiDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Chunxia MaoDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Shanshan LiuDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Yujie XuDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Han XuDepartment of Hematology Faculty of Medicine Qingdao University The Affiliated Hospital of Qingdao University Qingdao China.ORCID https://orcid.org/0000-0002-6158-1588
Xianqi FengDepartment of Hematology The Affiliated Hospital of Qingdao University Qingdao China.
Qingdao University · CNJeonbuk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the clinical characteristics, diagnosis, and treatment of chronic lymphocytic leukemia with secondary pancytopenia. Here, a case of pancytopenia secondary to chronic lymphocytic leukemia is reported. Additionally, a review of relevant chronic lymphocytic leukemia literature was conducted to summarize its diagnosis, clinical characteristics, treatment history, and experience. After treatment with cyclosporine A, the patient's chronic lymphocytic leukemia continued to resolve, and hematopoiesis returned to normal. Cyclosporine A therapy resulted in improved patient outcomes. However, the mechanism by which cyclosporine A rebuilds the immune microenvironment and its antileukemia effect in the body remains to be studied.

Indexed as

case reportchronic lymphoblastic leukemiacyclosporine Aimmune microenvironment

Identifiers

PMID35310307
PMCPMC8908086
OpenAlexW4220658832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.