Evidence map›Paper›PMID 35310196›Full record

ArticleJournal of healthcare engineering2022

miR-195 Inhibits Proliferation and Enhances Apoptosis of OSCC Cells via Targeting TLR4.

Jianguo Wang, Renyou Song, Chunmei Wang, Shuangsheng Zhang, Yanqi Zhang, Yanlong Zhu, Gang Zhao

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jianguo WangDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.
Renyou SongDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.
Chunmei WangDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.
Shuangsheng ZhangDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.
Yanqi ZhangDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.
Yanlong ZhuDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.
Gang ZhaoDepartment of Oral and Maxillofacial Surgery, Jiamusi University Affiliated Stomatological Hospital, Jiamusi, China.ORCID 0000-0001-7263-3665
Jiamusi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this research was to assess the function of microribonucleic acid (miR)-195 in the apoptosis and proliferation of oral squamous cell carcinoma (OSCC) cells as well as its action mechanism. The downstream target protein of miR-195 was predicted using the biological software. A quantitative polymerase chain reaction (qPCR) was implemented to examine the changes in expressions of miR-195 and its target protein toll-like receptor 4 (TLR4) in OSCC cell lines (TSCCA, Tca8223, Tb3.1, and CAL-27) and normal adult human gingival fibroblasts (HGFs), and the relation between their expressions was assessed. The expressions of phosphorylated proteins in nuclear factor-

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMicroRNAsMouth NeoplasmsAdultApoptosisCell ProliferationHumansNF-kappa BSignal TransductionSquamous Cell Carcinoma of Head and NeckToll-Like Receptor 4MicroRNAsMIRN195 microRNA, humanNF-kappa BTLR4 protein, humanToll-Like Receptor 4

Identifiers

PMID35310196
PMCPMC8926532
OpenAlexW4220824536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.