Evidence map›Paper›PMID 35310131›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2022

Persistent SARS-CoV-2 antigen presence in multiple organs of a naturally infected cat from Brazil.

Samar Afif Jarrah, Louise Bach Kmetiuk, Otávio Valério de Carvalho, Alessandra Tammy Hayakawa Ito de Sousa, Valeria Regia Franco Souza, Luciano Nakazato, Edson Moleta Colodel, Andrea Pires Dos Santos, Christina Pettan-Brewer, Rosane Christine Hahn and 6 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Samar Afif JarrahDepartment of Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, MG, Brazil.
Louise Bach KmetiukGraduate College of Molecular Biology, Federal University of Paraná, Curitiba, PR, Brazil.
Otávio Valério de CarvalhoGraduate College of Molecular Biology, Federal University of Paraná, Curitiba, PR, Brazil.
Alessandra Tammy Hayakawa Ito de SousaDepartment of Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, MG, Brazil.
Valeria Regia Franco SouzaDepartment of Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, MG, Brazil.
Luciano NakazatoDepartment of Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, MG, Brazil.
Edson Moleta ColodelDepartment of Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, MG, Brazil.
Andrea Pires Dos SantosDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Christina Pettan-BrewerDepartment of Comparative Medicine, School of Medicine, University of Washington, Seattle, Washington, USA.
Rosane Christine HahnMedical Science Faculty, Federal University of Mato Grosso, Cuiabá, MT, Brazil.
Renata Dezengrini SlhessarenkoJúlio Muller University Hospital, Federal University of Mato Grosso, Cuiabá, MT, Brazil.
Daniel Guimarães UbialiDepartment of Epidemiology and Public Health, Veterinary Institute, Federal Rural University of Rio de Janeiro, Seropedica, RJ, Brazil.
Asheley Henrique Barbosa PereiraDepartment of Epidemiology and Public Health, Veterinary Institute, Federal Rural University of Rio de Janeiro, Seropedica, RJ, Brazil.ORCID 0000-0001-9704-9801
Helio Autran de MoraisDepartment of Clinical Sciences, Oregon State University, Corvallis, OR, United States.
Alexander Welker BiondoDepartment of Veterinary Medicine, Federal University of Paraná, Curitiba, PR, Brazil.ORCID 0000-0002-4182-5821
Valéria DutraDepartment of Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, MG, Brazil.
Universidade Federal de Mato Grosso · BRUniversidade Federal do Paraná · BRUniversidade Federal Rural do Rio de Janeiro · BROregon State University · USPurdue University West Lafayette · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of the disease coronavirus 2019 (COVID-19) in humans. SARS-CoV-2 has been identified in cats with or without clinical signs. Case presentation: We describe the pathological and molecular findings in a six-month-old asymptomatic cat with SARS-CoV-2 infection from Brazil, belonging to a human family with COVID-19 cases. The pool of nasopharynx and oropharynx swabs at day zero tested positive by RT-qPCR for SARS-CoV-2. No amplification resulted from molecular testing performed on days 7 and 14. The cat was hit by a car and died 43 days after the molecular diagnosis. Immunohistochemistry at Conclusion: The present study has highlighted the possibility that viral antigens can be detected by immunohistochemistry in multiple organs six weeks after infection, although the same tissues tested negative by RT-PCR.

Indexed as

CatsCoronavirusDisease transmissionPetsSARS-CoV-2

Identifiers

PMID35310131
PMCPMC8906534
OpenAlexW4220975923

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.