Evidence map›Paper›PMID 35309657›Full record

ArticleJournal of family medicine and primary care2022

Clinical experience of tocilizumab treatment among a cohort of patients with COVID-19 infection from Western India.

Prince D Surana, Rupesh Nayak, Arif Sheikh, Pradnya Haldankar, Jyoti Kale

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Prince D SuranaDepartment of Internal Medicine and Critical Care, Surana Sethia Hospital, Suman Nagar Sion Trombay Road Chembur, Mumbai, India.
Rupesh NayakDepartment of Internal Medicine and Critical Care, Surana Sethia Hospital, Suman Nagar Sion Trombay Road Chembur, Mumbai, India.
Arif SheikhDepartment of Internal Medicine and Critical Care, Surana Sethia Hospital, Suman Nagar Sion Trombay Road Chembur, Mumbai, India.
Pradnya HaldankarDepartment of Anesthesia and Critical Care, MPCT Hospital, Sector - 4, Sanpada, Navi Mumbai, Maharashtra, India.
Jyoti KaleDepartment of Anesthesia and Critical Care, MPCT Hospital, Sector - 4, Sanpada, Navi Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Initiation of tocilizumab (TCZ) treatment in patients with coronavirus disease 2019 (COVID-19) during the early phases of cytokine storm is crucial. This study evaluated the clinical experience of TCZ use in the treatment of patients with COVID-19. Methods: This retrospective observational study included patients (>18 years) with confirmed COVID19 treated with TCZ alone/in combination with other drugs. Data related to demographics, clinical characteristics, radiological parameters, oxygen/ventilator/vasopressor support, treatment parameters, laboratory investigations pre- and post-TCZ treatment, and clinical outcomes were retrieved from medical records. Results: Out of 95 patients (mean age, 55 years), 68.4% and 31.6% of patients had moderate and severe COVID-19 disease, respectively. The mean time to TCZ administration from symptom onset was 8.7 days. At the time of admission, the mean oxygen saturation (SpO Conclusion: Tocilizumab administration during earlier phase of cytokine storm syndrome leads to reversal of abnormal SpO

Indexed as

Cytokine storm syndromeinflammatory markersmoderate and severeoxygen saturationTCZ treatment

Identifiers

PMID35309657
PMCPMC8930122
OpenAlexW4210805408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.