Evidence map›Paper›PMID 35309526›Full record

ArticleBiology of sport2022

Effects of melatonin ingestion on physical performance and biochemical responses following exhaustive running exercise in soccer players.

Mohamed Amine Farjallah, Ahmed Graja, Lobna Ben Mahmoud, Kais Ghattassi, Mariem Boudaya, Tarak Driss, Kamel Jamoussi, Zouheir Sahnoun, Nizar Souissi, Omar Hammouda

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PubMed Full text at PMC Publisher
In one paragraph

Article in Biology of sport, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 5 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mohamed Amine FarjallahResearch Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia.
Ahmed GrajaResearch Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia.
Lobna Ben MahmoudDepartment of Pharmacology, Faculty of Medicine, University of Sfax, Sfax, Tunisia.
Kais GhattassiResearch Unit, Education, Motricity, Sport and Health, UR15JS01, High Institute of Sport and Physical Education, University of Sfax, Tunisia.
Mariem BoudayaBiochemistry Laboratory, CHU Hedi Chaker, University of Sfax, Tunisia.
Tarak DrissInterdisciplinary Laboratory in Neurosciences, Physiology and Psychology: Physical Activity, Health and Learning (LINP2-APSA), UPL, Paris Nanterre University, UFR STAPS, Nanterre France.
Kamel JamoussiBiochemistry Laboratory, CHU Hedi Chaker, University of Sfax, Tunisia.
Zouheir SahnounDepartment of Pharmacology, Faculty of Medicine, University of Sfax, Sfax, Tunisia.
Nizar Souissi"Physical Activity, Sport and Health" Research Unit, UR18JS01, National Sport Observatory, Tunis, Tunisia.
Omar HammoudaResearch Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia.
University of Sfax · TNHopital Universitaire Hedi Chaker · TNUniversité Paris Nanterre · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant supplementation has become a common practice among athletes to boost sport achievement. Likewise, melatonin (MEL) has been ingested as an ergogenic aid to improve physical performance. To date, no study has checked whether the multiple beneficial effects of MEL have an outcome during a maximum running exercise until exhaustion. Therefore, the present study aimed to evaluate the effect of MEL ingestion on physical performance and biochemical responses (i.e., oxidative stress) during exhaustive exercise. In a double blind randomized study, thirteen professional soccer players [age: 17.5 ± 0.8 years, body mass: 70.3 ± 3.9 kg, body height: 1.80 ± 0.08 m; maximal aerobic speed (MAS): 16.85 ± 0.63 km/h; mean ± standard deviation], members of a first league squad, performed a running exercise until exhaustion at 100% of MAS, after either MEL or placebo ingestion. Physical performance was assessed, and blood samples were obtained at rest and following the exercise. Compared to placebo, MEL intake prevented the increase in oxidative stress markers (i.e., malondialdehyde), alleviated the alteration of antioxidant status (i.e., glutathione peroxidase, uric acid and total bilirubin) and decreased post-exercise biomarkers of muscle damage (i.e., creatine kinase and lactate dehydrogenase) (p < 0.05). However, physical performance was not affected by MEL ingestion (p > 0.05). In conclusion, acute MEL intake before a maximal running exercise protected athletes from oxidative stress and cellular damage but without an effect on physical performance.

Indexed as

Cellular damageMelatonin antioxidantOxidative stressTime to exhaustion

Identifiers

PMID35309526
PMCPMC8919877
OpenAlexW3178672275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.