Evidence map›Paper›PMID 35309464›Full record

ArticleACS omega2022

Deciphering Black Extrinsic Tooth Stain Composition in Children Using Metaproteomics.

Christophe Hirtz, Atef Mahmoud Mannaa, Estelle Moulis, Olivier Pible, Robin O'Flynn, Jean Armengaud, Virginie Jouffret, Camille Lemaistre, Gabriel Dominici, Alex Yahiaoui Martinez and 8 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Christophe HirtzUniv Montpellier, INM, IRMB, INSERM, CHU Montpellier, CNRS, Montpellier 34070, France.ORCID https://orcid.org/0000-0002-7313-0629
Atef Mahmoud MannaaHigher Institute of Engineering and Technology, New Borg AlArab City 21934, Alexandria, Egypt.ORCID https://orcid.org/0000-0001-8631-4737
Estelle MoulisU.F.R. d'Odontologie, Département de pédodontie, 545, Avenue du Professeur Jean-Louis Viala, Montpellier Cedex 5 34 193, France.
Olivier PibleLaboratoire Innovations Technologiques pour la Détection et le Diagnostic (Li2D), Université de Montpellier, Bagnols-sur-Cèze F-30207, France.
Robin O'FlynnU.F.R. d'Odontologie, Département de pédodontie, 545, Avenue du Professeur Jean-Louis Viala, Montpellier Cedex 5 34 193, France.
Jean ArmengaudLaboratoire Innovations Technologiques pour la Détection et le Diagnostic (Li2D), Université de Montpellier, Bagnols-sur-Cèze F-30207, France.ORCID https://orcid.org/0000-0003-1589-445X
Virginie JouffretLaboratoire Innovations Technologiques pour la Détection et le Diagnostic (Li2D), Université de Montpellier, Bagnols-sur-Cèze F-30207, France.
Camille LemaistreU.F.R. d'Odontologie, Département de pédodontie, 545, Avenue du Professeur Jean-Louis Viala, Montpellier Cedex 5 34 193, France.
Gabriel DominiciU.F.R. d'Odontologie, Département de pédodontie, 545, Avenue du Professeur Jean-Louis Viala, Montpellier Cedex 5 34 193, France.
Alex Yahiaoui MartinezVirulence Bactérienne et Infections Chroniques, INSERM U1047, Univ Montpellier, Department of Microbiology and Hospital Hygiene, Nîmes University Hospital, Nîmes 30029, France.
Catherine Dunyach-RemyVirulence Bactérienne et Infections Chroniques, INSERM U1047, Univ Montpellier, Department of Microbiology and Hospital Hygiene, Nîmes University Hospital, Nîmes 30029, France.
Laurent TiersUniv Montpellier, INM, IRMB, INSERM, CHU Montpellier, CNRS, Montpellier 34070, France.
Jean-Philippe LavigneVirulence Bactérienne et Infections Chroniques, INSERM U1047, Univ Montpellier, Department of Microbiology and Hospital Hygiene, Nîmes University Hospital, Nîmes 30029, France.
Paul TraminiU.F.R. d'Odontologie, Département de pédodontie, 545, Avenue du Professeur Jean-Louis Viala, Montpellier Cedex 5 34 193, France.
Marie-Christine GoldsmithU.F.R. d'Odontologie, Département de pédodontie, 545, Avenue du Professeur Jean-Louis Viala, Montpellier Cedex 5 34 193, France.
Sylvain LehmannUniv Montpellier, INM, IRMB, INSERM, CHU Montpellier, CNRS, Montpellier 34070, France.
Dominique Deville de PérièreUniv Montpellier, INM, IRMB, INSERM, CHU Montpellier, CNRS, Montpellier 34070, France.
Jerome VialaretUniv Montpellier, INM, IRMB, INSERM, CHU Montpellier, CNRS, Montpellier 34070, France.
Université de Montpellier · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study focuses on the use of a metaproteomic approach to analyze Black Extrinsic Tooth Stains, a specific type of pigmented extrinsic substance. Metaproteomics is a powerful emerging technology that successfully enabled human protein and bacterial identification of this specific dental biofilm using high-resolution tandem mass spectrometry. A total of 1600 bacterial proteins were identified in black stain (BS) samples and 2058 proteins in dental plaque (DP) samples, whereas 607 and 582 human proteins were identified in BS and DP samples, respectively. A large diversity of bacteria genera (142) in BS and DP was identified, showing a high prevalence of Rothia, Kingella, Neisseria, and Pseudopropionibacterium in black stain samples. In this work, the high diversity of the dental microbiota and its proteome is highlighted, including significant differences between black stain and dental plaque samples.

Identifiers

PMID35309464
PMCPMC8928488
OpenAlexW4214561679

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.